Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.59 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5526571 | 1.00 | EPHX2 (0.59) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| SCHEMBL18784675 | 0.94 | EPHX2 (0.56) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| SCHEMBL5139457 | 0.91 | EPHX2 (0.66) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| SCHEMBL5139456 | 0.91 | EPHX2 (0.66) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| SCHEMBL20124225 | 0.87 | GNAI3 (0.49) | ALDH1A1MEN1KMT2A | |
| SCHEMBL13670134 | 0.86 | EPHX2 (0.60) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| SCHEMBL18784665 | 0.86 | GNAI3 (0.58) | KDM4EMEN1KMT2A | |
| SCHEMBL18784666 | 0.86 | GNAI3 (0.58) | KDM4EMEN1KMT2A | |
| SCHEMBL8439737 | 0.83 | CASP2 (0.56) | EPHX2KDM4E | |
| SCHEMBL11981498 | 0.83 | SMN1; SMN2 (0.50) | KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513538-A4 | NOVEL METHODS FOR THE DELIVERY OF POLYNUCLEOTIDES TO CELLS | MIRUS BIO CORP (US) | 2007-08-22 | — | — | EP | disclosed |
| EP-1513538-A2 | NOVEL METHODS FOR THE DELIVERY OF POLYNUCLEOTIDES TO CELLS | Mirus Corporation (US) | 2005-03-16 | — | — | EP | disclosed |
| US-20030235916-A1 | Novel methods for the delivery of polynucleotides to cells | ROCHE MADISON INC. | 2003-12-25 | — | — | US | disclosed |
| WO-2003106636-A2 | NOVEL METHODS FOR THE DELIVERY OF POLYNUCLEOTIDES TO CELLS | MIRUS CORPORATION (US) | 2003-12-24 | — | — | WO | disclosed |