Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.51 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.51 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.51 |
| ▸ | PRCP | P42785 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.47 |
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24412633 | 0.89 | CASP2 (0.65) | CASP2NAAAGNAI3GNAO1GNAI1 | |
| SCHEMBL24412952 | 0.89 | CASP2 (0.65) | CASP2NAAAGNAI3GNAO1GNAI1 | |
| SCHEMBL18784665 | 0.88 | GNAI3 (0.58) | CASP2NAAAGNAI3GNAO1GNAI1 | |
| SCHEMBL18784666 | 0.88 | GNAI3 (0.58) | CASP2NAAAGNAI3GNAO1GNAI1 | |
| SCHEMBL20124225 | 0.87 | GNAI3 (0.49) | CASP2NAAAGNAI3GNAO1GNAI1 | |
| SCHEMBL11981498 | 0.85 | SMN1; SMN2 (0.50) | CASP2GNAI3GNAO1GNAI1KDM4E | |
| SCHEMBL24412716 | 0.85 | CASP2 (0.59) | CASP2NAAAGNAI3GNAO1GNAI1 | |
| SCHEMBL17817099 | 0.85 | KDM4E (0.62) | CASP2NAAAGNAI3GNAO1GNAI1 | |
| SCHEMBL3477552 | 0.85 | CASP2 (0.59) | CASP2NAAAGNAI3GNAO1GNAI1 | |
| SCHEMBL7862964 | 0.84 | SIGMAR1 (0.61) | CASP2NAAAGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757560-B1 | OPHTHALMIC COMPOSITIONS COMPRISING AMIDOAMINES | ALCON LAB INC (US) | 1999-12-22 | — | — | EP | disclosed |
| EP-0757560-A1 | USE OF AMIDOAMINES IN OPHTHALMIC COMPOSITIONS | ALCON LABORATORIES, INC. (US) | 1997-02-12 | — | — | EP | disclosed |
| US-5573726-A | DISINFECTING CONTACT LENSES | ALCON LABORATORIES, INC. (US) | 1996-11-12 | — | — | US | disclosed |
| WO-1996026747-A2 | USE OF AMIDOAMINES IN OPHTHALMIC COMPOSITIONS | ALCON LABORATORIES, INC. (US) | 1996-09-06 | — | — | WO | disclosed |