SCHEMBL5527342

SCHEMBL5527342

O=C(c1ccc(F)cc1)c1ccc2cc(C(=O)c3ccc(F)cc3)ccc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.57
NPC1 O15118 5/20 0.55
RAB9A P51151 3/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
HSD17B14 Q9BPX1 1/20 0.55
CES2 O00748 2/20 0.52
CES1 P23141 2/20 0.52
CLK1 P49759 1/20 0.50
DYRK1A Q13627 1/20 0.50
DYRK1B Q9Y463 1/20 0.50
ALDH1A1 P00352 2/20 0.48
TSHR P16473 2/20 0.48
MAPK1 P28482 2/20 0.48
LMNA P02545 1/20 0.48
ALPG P10696 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
KDM4E B2RXH2 1/20 0.48
TP53 P04637 1/20 0.48
MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30542686 1.00 LTA4H (0.57) LTA4HNPC1RAB9AMEN1KMT2A
SCHEMBL9789579 0.96 LTA4H (0.53) LTA4HNPC1RAB9AMEN1KMT2A
SCHEMBL9407151 0.93 LTA4H (0.55) LTA4HNPC1RAB9AMEN1KMT2A
SCHEMBL11706745 0.92 HSD17B14 (0.67) LTA4HNPC1RAB9AMEN1KMT2A
SCHEMBL8416716 0.90 MEN1 (0.71) LTA4HNPC1RAB9AMEN1KMT2A
SCHEMBL21679476 0.86 KDM4E (0.62) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL29869451 0.86 KDM4E (0.62) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL238259 0.85 LTA4H (0.73) LTA4HNPC1RAB9ACES2CES1
SCHEMBL8572071 0.85 LTA4H (0.73) LTA4HNPC1RAB9ACES2CES1
SCHEMBL1736339 0.85 LTA4H (0.73) LTA4HNPC1RAB9ACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116640298-A Method for preparing benzene end-capped polyaryletherketone by end capping 山东君昊高性能聚合物有限公司 2023-08-25 CN disclosed
CN-103554479-B A kind of polyaryletherketone containing N substituted benzimidazole group and preparation method thereof SOUTHWEST UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2015-09-23 CN disclosed
US-8173349-B2 Photosensitive resin composition, polymer compound, method of forming a pattern, and electronic device FUJIFILM CORPORATION (JP) 2012-05-08 US disclosed
US-8173349-B2 Photosensitive resin composition, polymer compound, method of forming a pattern, and electronic device FUJIFILM CORPORATION (JP) 2012-05-08 US disclosed
US-20100080963-A1 PHOTOSENSITIVE RESIN COMPOSITION, POLYMER COMPOUND, METHOD OF FORMING A PATTERN, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-20100080963-A1 PHOTOSENSITIVE RESIN COMPOSITION, POLYMER COMPOUND, METHOD OF FORMING A PATTERN, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
EP-0428743-B1 POLY(ARYLENE ETHER KETONE), METHOD OF ITS PRODUCTION, AND ITS USE TEIJIN LTD (JP) 1999-09-08 EP disclosed
US-5847032-A Sulfo-pendent aryletherketone copolymers film containing NLO chromophore THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1998-12-08 US disclosed
US-5837783-A Sulfo-pendent aryletherketone polymer film containing NLO chromophore THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1998-11-17 US disclosed
US-5290906-A Polymers from hydroquinone and 2,6-bisUp-fluorobenzoyle naphthalene for films and fibers with tensile strength TEIJIN LIMITED (JP) 1994-03-01 US disclosed
EP-0428743-A1 POLY(ARYLENE ETHER KETONE), METHOD OF ITS PRODUCTION, AND ITS USE TEIJIN LIMITED (JP) 1991-05-29 EP disclosed
WO-1990015836-A1 SELF-POLYMERIZABLE PHENYLQUINOXALINES THE UNIVERSITY OF AKRON (US) 1990-12-27 WO disclosed
US-4959423-A IMPROVED CRYSTALLIZATION RATES AMOCO CORPORATION (US) 1990-09-25 US disclosed
US-4910289-A Crystal structure; blend with poly(arylene sulfide) AMOCO CORPORATION (US) 1990-03-20 US disclosed
US-4898983-A FRIEDEL-CRAFTS PROCESS; LEWIS ACIDS, BY-PRODUCT INHIBITION; ACID HALIDES, ACTIVE HYDROGEN AROMATIC COMPONENTS; CONTROLLING AGENTS RAYCHEM LIMITED (GB) 1990-02-06 US disclosed
US-4861915-A Poly (aryl ether ketone) block copolymers AMOCO CORPORATION (US) 1989-08-29 US disclosed
US-4786694-A Poly(aryl ether ketone) block copolymers AMOCO CORPORATION (US) 1988-11-22 US disclosed
EP-0262919-A2 Preparation of aryl carbonyl compounds RAYCHEM LIMITED (GB) 1988-04-06 EP disclosed
EP-0143407-B1 PROCESS FOR PREPARING AROMATIC POLYETHERS HOECHST AKTIENGESELLSCHAFT (DE) 1986-11-12 EP disclosed
EP-0143407-A2 Process for preparing aromatic polyethers HOECHST AKTIENGESELLSCHAFT (DE) 1985-06-05 EP disclosed