SCHEMBL9407151

SCHEMBL9407151

O=C(c1ccc(F)cc1)c1ccc2ccc(C(=O)c3ccc(F)cc3)cc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.55
HSD17B14 Q9BPX1 1/20 0.53
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
NPC1 O15118 5/20 0.48
RAB9A P51151 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
ALDH1A1 P00352 2/20 0.47
TSHR P16473 2/20 0.47
MAPK1 P28482 2/20 0.47
LMNA P02545 1/20 0.47
ALPG P10696 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
KDM4E B2RXH2 1/20 0.47
TP53 P04637 1/20 0.47
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
CASP1 P29466 1/20 0.47
CASP7 P55210 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9789579 0.94 LTA4H (0.53) LTA4HHSD17B14CES2CES1NPC1
SCHEMBL30542686 0.93 LTA4H (0.57) LTA4HHSD17B14CES2CES1NPC1
SCHEMBL5527342 0.93 LTA4H (0.57) LTA4HHSD17B14CES2CES1NPC1
SCHEMBL11706745 0.90 HSD17B14 (0.67) LTA4HHSD17B14CES2CES1NPC1
SCHEMBL8416716 0.84 MEN1 (0.71) LTA4HHSD17B14NPC1RAB9AMEN1
SCHEMBL1736339 0.83 LTA4H (0.73) LTA4HCES2CES1NPC1RAB9A
SCHEMBL8572071 0.83 LTA4H (0.73) LTA4HCES2CES1NPC1RAB9A
SCHEMBL238259 0.83 LTA4H (0.73) LTA4HCES2CES1NPC1RAB9A
SCHEMBL1070238 0.81 LTA4H (0.64) LTA4HCES2CES1NPC1RAB9A
SCHEMBL29983601 0.81 LTA4H (0.70) LTA4HCES2CES1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9803050-B2 Dispersant for use in synthesis of polyaryletherketones TICONA LLC (US) 2017-10-31 US disclosed
WO-2016057253-A1 DISPERSANT FOR USE IN SYNTHESIS OF POLYARYLETHERKETONES TICONA LLC (US) 2016-04-14 WO disclosed
US-20160102173-A1 Dispersant for Use in Synthesis of Polyaryletherketones TICONA LLC 2016-04-14 US disclosed
US-5290906-A Polymers from hydroquinone and 2,6-bisUp-fluorobenzoyle naphthalene for films and fibers with tensile strength TEIJIN LIMITED (JP) 1994-03-01 US disclosed
US-5191056-A Molding materials TEIJIN LIMITED (JP) 1993-03-02 US disclosed
US-5126427-A For stable solutions in halogenated hydrocarbons, solvent resistance, thermal poroperties, molding materials, coatings CIBA-GEIGY CORPORATION (US) 1992-06-30 US disclosed
EP-0451104-A2 Soluble polyarylenetherketones CIBA-GEIGY AG (CH) 1991-10-09 EP disclosed
EP-0447358-A2 Soluble polyarylene ether sulfones CIBA-GEIGY AG (CH) 1991-09-18 EP disclosed
US-5037936-A Bis(acid chloride) terminated polyaryl ether ketone oligomer AMOCO CORPORATION (US) 1991-08-06 US disclosed
EP-0428743-A1 POLY(ARYLENE ETHER KETONE), METHOD OF ITS PRODUCTION, AND ITS USE TEIJIN LIMITED (JP) 1991-05-29 EP disclosed
US-4959423-A IMPROVED CRYSTALLIZATION RATES AMOCO CORPORATION (US) 1990-09-25 US disclosed
US-4910289-A Crystal structure; blend with poly(arylene sulfide) AMOCO CORPORATION (US) 1990-03-20 US disclosed
US-4861915-A Poly (aryl ether ketone) block copolymers AMOCO CORPORATION (US) 1989-08-29 US disclosed
US-4786694-A Poly(aryl ether ketone) block copolymers AMOCO CORPORATION (US) 1988-11-22 US disclosed