Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 3/20 | 0.48 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | BACE1 | P56817 | 3/20 | 0.47 |
| ▸ | HTR1B | P28222 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5532963 | 0.90 | NCF1 (0.58) | HTR1DNCF1HTR1BHTR1AKCNH2 | |
| SCHEMBL5529129 | 0.89 | HTR1D (0.52) | HTR1DNCF1BCHEACHEBACE1 | |
| SCHEMBL5529815 | 0.88 | NCF1 (0.51) | HTR1DNCF1HTR1BHTR1ASMN1; SMN2 | |
| SCHEMBL14437441 | 0.88 | NCF1 (0.51) | HTR1DNCF1HTR1BHTR1ASMN1; SMN2 | |
| SCHEMBL5531659 | 0.86 | HTR1D (0.57) | HTR1DNCF1ACHEHTR1BHTR1A | |
| SCHEMBL13945423 | 0.84 | HTR1D (0.50) | HTR1DNCF1HTR1BHTR1AKCNH2 | |
| SCHEMBL5532964 | 0.84 | HRH3 (0.58) | HTR1DNCF1HTR1BHTR1ASMN1; SMN2 | |
| SCHEMBL5532956 | 0.83 | MCHR1 (0.53) | HTR1DNCF1HTR1BHTR1AKCNH2 | |
| SCHEMBL13945359 | 0.83 | HTR1D (0.51) | HTR1DNCF1HTR1BHTR1ASMN1; SMN2 | |
| SCHEMBL5531742 | 0.83 | SSTR5 (0.54) | HTR1DBCHEACHEHTR1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | KCNN3, KCNN2, HCN3 | HTR1D 1094/4885NCF1 2805/4885BCHE 1468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.