Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | RBP4 | P02753 | 6/20 | 0.44 |
| ▸ | IDH2 | P48735 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5525363 | 0.87 | HRH4 (0.46) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL5519910 | 0.85 | RBP4 (0.43) | KDM4EHSD17B10HPGDCYP2C19TSHR | |
| SCHEMBL1420176 | 0.84 | RBP4 (0.42) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL5524235 | 0.83 | ALDH1A1 (0.45) | KDM4EHSD17B10HPGDTSHRGAA | |
| SCHEMBL13494044 | 0.82 | KDM4E (0.81) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL5528147 | 0.81 | PIK3CA (0.47) | KDM4EHSD17B10NPSR1ATMALDH1A1 | |
| SCHEMBL5559566 | 0.79 | KDM4E (0.58) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL5525405 | 0.79 | CKS1B (0.49) | RBP4TTR | |
| SCHEMBL725443 | 0.74 | KDM4E (0.71) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL5844330 | 0.74 | KDM4E (1.00) | KDM4EHSD17B10USP2HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | POLI, POLB, POLA1 | KDM4E 676/4885HSD17B10 1793/4885USP2 3446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.