Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 10/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5519910 | 0.87 | RBP4 (0.43) | LMNAHTTHSD17B10KDM4EALDH1A1 | |
| SCHEMBL5524235 | 0.86 | ALDH1A1 (0.45) | POLBLMNAHTTHSD17B10KDM4E | |
| SCHEMBL5528861 | 0.85 | ALDH1A1 (0.47) | PIK3CAPOLBLMNAHTTHSD17B10 | |
| SCHEMBL3113600 | 0.81 | KMT2A (0.60) | PIK3CAPOLBLMNAHTTHSD17B10 | |
| SCHEMBL5525363 | 0.81 | HRH4 (0.46) | HSD17B10KDM4EALDH1A1NPSR1 | |
| SCHEMBL5527465 | 0.81 | KDM4E (0.58) | POLBHSD17B10KDM4EALDH1A1ATM | |
| SCHEMBL3997510 | 0.81 | POLB (0.52) | PIK3CAPOLBLMNAHTTHSD17B10 | |
| SCHEMBL1271891 | 0.80 | KMO (0.61) | PIK3CAPOLBLMNAHTTHSD17B10 | |
| SCHEMBL13848187 | 0.78 | PIK3CA (0.56) | PIK3CAPOLBLMNAHTTHSD17B10 | |
| SCHEMBL1420176 | 0.78 | RBP4 (0.42) | HSD17B10KDM4EL3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | POLI, POLB, POLA1 | PIK3CA 164/4885POLB 2/4885LMNA 3249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.