SCHEMBL15501263

SCHEMBL15501263

CC(=S)N/N=C(\C)c1cccc(/C(C)=N/NC(N)=S)n1

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.54
METTL3 Q86U44 1/20 0.54
CTSK P43235 1/20 0.53
HSP90AA1 P07900 1/20 0.52
CTSL P07711 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13826734 0.95 ATM (0.59) ATMMETTL3CTSKHSP90AA1CTSL
SCHEMBL29010741 0.95 ATM (0.59) ATMMETTL3CTSKHSP90AA1CTSL
SCHEMBL31192684 0.88 ATM (0.51) ATMMETTL3CTSKHSP90AA1CTSL
SCHEMBL5527648 0.88 ATM (0.51) ATMMETTL3CTSKHSP90AA1CTSL
SCHEMBL5527650 0.88 ATM (0.51) ATMMETTL3CTSKHSP90AA1CTSL
SCHEMBL6743847 0.78 HSP90AA1 (0.49) ATMMETTL3CTSKHSP90AA1
SCHEMBL6743841 0.78 HSP90AA1 (0.49) ATMMETTL3CTSKHSP90AA1
SCHEMBL13826733 0.78 LMNA (0.59) HSP90AA1
SCHEMBL941093 0.77 TOP2A (0.70) ATMMETTL3CTSKHSP90AA1
SCHEMBL941092 0.77 TOP2A (0.70) ATMMETTL3CTSKHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9302019-B2 Fe(II) sequestering agents and uses thereof THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2016-04-05 US disclosed
US-20140072517-A1 FE(II) SEQUESTERING AGENTS AND USES THEREOF THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW (US) 2014-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140072517-A1 FE(II) SEQUESTERING AGENTS AND USES THEREOF SLC40A1, SLC39A14, SLC39A3 ATM 2985/4885METTL3 2833/4885CTSK 1574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.