Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CASP6 | P55212 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL589663 | 0.83 | CTSB (1.00) | CTSBMAPTKMT2AMEN1KDM4E | |
| SCHEMBL5921938 | 0.79 | CTSB (0.61) | CTSBMAPTKMT2AMEN1KDM4E | |
| Methoxymethane SCHEMBL7777573 | 0.77 | CTSB (0.86) | CTSBMAPTKMT2AMEN1KDM4E | |
| Nitric Acid SCHEMBL14696120 | 0.76 | VCP (0.46) | MAPTKMT2AMEN1HTTLMNA | |
| Benzoic Acid SCHEMBL20788024 | 0.73 | CTSB (0.77) | CTSBMAPTKMT2AMEN1KDM4E | |
| SCHEMBL2769398 | 0.72 | CTSB (0.78) | CTSBMAPTKMT2AMEN1KDM4E | |
| P-Nitrophenol SCHEMBL11305882 | 0.72 | MAPT (0.54) | MAPTKMT2AMEN1HTTLMNA | |
| SCHEMBL7788656 | 0.72 | TDP1 (0.80) | CTSBMAPTKMT2AMEN1KDM4E | |
| SCHEMBL1552872 | 0.71 | MAPT (1.00) | CTSBMAPTKMT2AMEN1KDM4E | |
| Nitroxoline SCHEMBL29363027 | 0.71 | MAPT (1.00) | CTSBMAPTKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844328-A2 | USE OF REVERSIBLE EXTENSION TERMINATOR IN NUCLEIC ACID SEQUENCING | Pacific Biosciences of California, Inc. (US) | 2007-10-17 | — | — | EP | disclosed |
| EP-1790202-A2 | APPARATUS AND METHOD FOR ANALYSIS OF MOLECULES | Pacific Biosciences of California, Inc. (US) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006083751-A2 | USE OF REVERSIBLE EXTENSION TERMINATOR IN NUCLEIC ACID SEQUENCING | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2006-08-10 | — | — | WO | disclosed |
| WO-2006044078-A2 | APPARATUS AND METHOD FOR ANALYSIS OF MOLECULES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2006-04-27 | — | — | WO | disclosed |