Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.45 |
| ▸ | PLK1 | P53350 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5520247 | 0.90 | SRD5A2 (0.41) | EPHX2NR1H4SMN1; SMN2RAB9ACOPS5 | |
| SCHEMBL5527724 | 0.89 | NPC1 (0.44) | EPHX2NR1H4MAPTNPC1RAB9A | |
| SCHEMBL5522346 | 0.86 | PLA2G10 (0.44) | EPHX2NR1H4SMN1; SMN2MAPTNPC1 | |
| SCHEMBL5527532 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPTNPC1RAB9ACOPS5 | |
| SCHEMBL5528374 | 0.84 | ALDH1A1 (0.45) | NR1H4SMN1; SMN2MAPTNPC1COPS5 | |
| SCHEMBL5522358 | 0.83 | RAB9A (0.51) | SMN1; SMN2MAPTNPC1RAB9ACOPS5 | |
| SCHEMBL5524260 | 0.83 | PPARA (0.40) | SMN1; SMN2MAPTRAB9ACOPS5HPGD | |
| SCHEMBL5522256 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTNPC1RAB9ACOPS5 | |
| SCHEMBL5527717 | 0.81 | TSHR (0.47) | EPHX2NR1H4SMN1; SMN2ALDH1A1XDH | |
| SCHEMBL5556176 | 0.81 | PLK1 (0.51) | EPHX2NR1H4PLK1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | POLI, POLB, POLA1 | EPHX2 2567/4885NR1H4 871/4885PLK1 240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.