Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 10/20 | 0.43 |
| ▸ | PPARD | Q03181 | 7/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5527688 | 0.87 | ALDH1A1 (0.43) | ALDH1A1NPC1GAAPPARAPPARD | |
| SCHEMBL5524260 | 0.87 | PPARA (0.40) | GAACOPS5PPARAPPARDSMN1; SMN2 | |
| SCHEMBL5528655 | 0.85 | ALDH1A1 (0.53) | ALDH1A1NPC1SMN1; SMN2MEN1MAPT | |
| SCHEMBL5520247 | 0.85 | SRD5A2 (0.41) | ALDH1A1GAASRD5A2COPS5SMN1; SMN2 | |
| SCHEMBL5527532 | 0.85 | SMN1; SMN2 (0.48) | ALDH1A1NPC1GAACOPS5SMN1; SMN2 | |
| SCHEMBL6183548 | 0.85 | ALDH1A1 (0.55) | ALDH1A1NPC1GAACOPS5PPARA | |
| SCHEMBL5522358 | 0.84 | RAB9A (0.51) | ALDH1A1NPC1GAACOPS5PPARA | |
| SCHEMBL5528465 | 0.84 | EPHX2 (0.45) | ALDH1A1NPC1COPS5PPARAPPARD | |
| SCHEMBL5522629 | 0.83 | LMNA (0.50) | PPARAPPARDPPARGNR1H4 | |
| SCHEMBL5522256 | 0.83 | SMN1; SMN2 (0.50) | ALDH1A1NPC1GAACOPS5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | POLI, POLB, POLA1 | ALDH1A1 2042/4885NPC1 3623/4885GAA 351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.