Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11672044 | 0.89 | LMNA (0.46) | LMNARIPK1AOC3ALDH1A1KDM4E | |
| SCHEMBL11673116 | 0.88 | ASAH1 (0.46) | LMNARIPK1ALDH1A1KDM4ESLC6A4 | |
| SCHEMBL348229 | 0.84 | LMNA (0.67) | LMNARIPK1AOC3ALDH1A1KDM4E | |
| SCHEMBL28617318 | 0.84 | LMNA (0.67) | LMNARIPK1AOC3ALDH1A1KDM4E | |
| SCHEMBL1295513 | 0.84 | LMNA (0.67) | LMNARIPK1AOC3ALDH1A1KDM4E | |
| SCHEMBL540695 | 0.84 | LMNA (0.67) | LMNARIPK1AOC3ALDH1A1KDM4E | |
| SCHEMBL21633858 | 0.82 | LMNA (0.48) | LMNARIPK1AOC3ALDH1A1KDM4E | |
| SCHEMBL6055125 | 0.81 | GAA (0.47) | ALDH1A1L3MBTL1CYP3A4MAPTTDP1 | |
| SCHEMBL20078695 | 0.81 | ALDH1A1 (0.43) | AOC3ALDH1A1KDM4EL3MBTL1CYP1A2 | |
| SCHEMBL27532713 | 0.81 | LMNA (0.52) | LMNARIPK1AOC3L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070102695-A1 | Crosslinkable substituted fluorene compounds and conjugated oligomers or polymers based thereon | DOW GLOBAL TECHNOLOGIES INC. | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070102695-A1 | Crosslinkable substituted fluorene compounds and conjugated oligomers or polymers based thereon | THEM6, PCNA, PARG | LMNA 2585/4885RIPK1 3653/4885AOC3 459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.