Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.46 |
| ▸ | RBP4 | P02753 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5528147 | 0.85 | PIK3CA (0.47) | ALDH1A1PIK3CANPSR1POLBMAPK1 | |
| SCHEMBL3997688 | 0.84 | ALDH1A1 (0.51) | ALDH1A1TSHRPIK3CANPSR1MTOR | |
| SCHEMBL13494000 | 0.83 | RBP4 (0.58) | ALDH1A1TSHRPIK3CANPSR1MTOR | |
| SCHEMBL11926409 | 0.82 | ALDH1A1 (0.49) | ALDH1A1TSHRPIK3CANPSR1MTOR | |
| SCHEMBL31705334 | 0.82 | ALDH1A1 (0.49) | ALDH1A1TSHRPIK3CANPSR1MTOR | |
| SCHEMBL5557945 | 0.80 | ALDH1A1 (0.47) | ALDH1A1TSHRPIK3CANPSR1MTOR | |
| SCHEMBL5520450 | 0.77 | CKS1B (0.46) | ALDH1A1TSHRRBP4HSD17B10 | |
| SCHEMBL7016486 | 0.76 | MEN1 (0.51) | ALDH1A1TSHRPIK3CANPSR1MTOR | |
| SCHEMBL30995422 | 0.76 | PIK3CA (0.51) | ALDH1A1PIK3CANPSR1MTORRBP4 | |
| SCHEMBL23304372 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TSHRPIK3CANPSR1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | POLI, POLB, POLA1 | ALDH1A1 2042/4885TSHR 3395/4885PIK3CA 164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.