SCHEMBL5529146

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5529539	0.83	PPARA (0.50)	KMT2AMAPTLMNACYP1A2ALDH1A1
	SCHEMBL15140360	0.83	PPARG (0.47)	NPSR1KMT2AMAPTMEN1LMNA
	SCHEMBL28203314	0.83	PPARG (0.47)	KMT2AMAPTMEN1LMNAALDH1A1
	SCHEMBL2106687	0.81	LMNA (0.60)	NPSR1KMT2AMAPTMEN1LMNA
	SCHEMBL10487619	0.81	LMNA (0.60)	NPSR1KMT2AMAPTMEN1LMNA
	SCHEMBL3369250	0.81	LMNA (0.60)	NPSR1KMT2AMAPTMEN1LMNA
	SCHEMBL11285398	0.81	CYP1A2 (0.40)	NPSR1KMT2AMAPTMEN1LMNA
	SCHEMBL21992537	0.79	NPSR1 (0.47)	NPSR1KMT2AMAPTMEN1LMNA
	SCHEMBL28549855	0.78	MAPT (0.39)	NPSR1KMT2AMAPTMEN1LMNA
	SCHEMBL27845044	0.78	PPARG (0.44)	NPSR1KMT2AMAPTMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.