Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.68 |
| ▸ | CTSL | P07711 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5529222 | 1.00 | ATM (0.68) | ATMMETTL3CTSLALDH1A1CTSK | |
| SCHEMBL5531911 | 0.87 | METTL3 (0.73) | ATMMETTL3CTSK | |
| SCHEMBL5531907 | 0.87 | METTL3 (0.73) | ATMMETTL3CTSK | |
| SCHEMBL940532 | 0.86 | ALDH1A1 (0.67) | ATMMETTL3CTSLALDH1A1CTSK | |
| Phenyl(Methyl)Thiosemicarbazone SCHEMBL14436799 | 0.82 | METTL3 (1.00) | ATMMETTL3ALDH1A1CTSK | |
| Acetophenone-Thiosemicarbazone SCHEMBL17666972 | 0.82 | METTL3 (1.00) | ATMMETTL3ALDH1A1CTSK | |
| Phenyl(Methyl)Thiosemicarbazone SCHEMBL757506 | 0.82 | METTL3 (1.00) | ATMMETTL3ALDH1A1CTSK | |
| SCHEMBL5526647 | 0.81 | ATM (0.73) | ATMMETTL3CTSLALDH1A1CTSK | |
| SCHEMBL5526650 | 0.81 | ATM (0.73) | ATMMETTL3CTSLALDH1A1CTSK | |
| SCHEMBL5516796 | 0.79 | ATM (0.69) | ATMMETTL3CTSLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197495-A1 | ANTI-PARASITIC COMPOUNDS AND METHODS OF THEIR USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-08-23 | — | — | US | disclosed |
| EP-1734939-A1 | ANTI-PARASITIC COMPOUNDS AND METHODS OF THEIR USE | The Regents of The University of California (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005087211-A1 | ANTI-PARASITIC COMPOUNDS AND METHODS OF THEIR USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197495-A1 | ANTI-PARASITIC COMPOUNDS AND METHODS OF THEIR USE | CYP51A1, TUBA3C, PIGO | ATM 4843/4885METTL3 4301/4885CTSL 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.