Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 6/20 | 1.00 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.85 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | CD44 | P16070 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29473102 | 1.00 | PNMT (1.00) | PNMTASIC3ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL29528420 | 0.98 | PNMT (0.96) | PNMTASIC3ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL1266299 | 0.98 | PNMT (0.96) | PNMTASIC3ADRA2AADRA2BADRA2C | |
| SCHEMBL505055 | 0.92 | ASIC3 (1.00) | PNMTASIC3ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL1017313 | 0.90 | ASIC3 (0.96) | PNMTASIC3ADRA2AADRA2BADRA2C | |
| SCHEMBL1849383 | 0.88 | PNMT (0.79) | PNMTASIC3ADRA2AADRA2BADRA2C | |
| SCHEMBL29573611 | 0.88 | PNMT (0.79) | PNMTASIC3ADRA2AADRA2BADRA2C | |
| SCHEMBL1264341 | 0.87 | PNMT (0.77) | PNMTASIC3ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL21753269 | 0.85 | PNMT (0.74) | PNMTASIC3ADRA2AADRA2BADRA2C | |
| SCHEMBL329957 | 0.82 | PNMT (0.69) | PNMTASIC3ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 411 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110294758-B | 2-substituted 5, 6-dihydropyrazolo [5, 1-alpha ] isoquinoline, derivatives and synthesis method thereof | 湘潭大学 | 2021-10-22 | — | — | CN | claimed |
| CN-109293569-B | Method for preparing formamide derivative through amine transfer reaction without participation of catalyst | 湘潭大学 | 2021-08-06 | — | — | CN | claimed |
| CN-107827817-B | Method for synthesizing formamide derivative through molybdenum catalytic formylation reaction | 湘潭大学 | 2020-03-13 | — | — | CN | claimed |
| CN-107827816-B | Method for synthesizing formamide derivative through graphene oxide catalytic formylation reaction | 湘潭大学 | 2020-01-10 | — | — | CN | claimed |
| CN-107892670-B | Method for synthesizing formamide derivative through cobalt-catalyzed formylation reaction | 湘潭大学 | 2019-12-13 | — | — | CN | claimed |
| CN-110294758-A | 2- replaces 5,6- dihydro-pyrazolo [5,1- α] isoquinolin, derivative and its synthetic method | 湘潭大学 | 2019-10-01 | — | — | CN | claimed |
| WO-2026106389-A1 | NMT INHIBITOR AND USE THEREOF | 주식회사 이노보테라퓨틱스 | 2026-05-21 | — | — | WO | disclosed |
| US-20260092053-A1 | KHK INHIBITORS | GILEAD SCIENCES INC (US) | 2026-04-02 | — | — | US | disclosed |
| US-20260092059-A1 | Broad Spectrum Antiviral Compositions and Methods | EVRYS BIO, LLC (US) | 2026-04-02 | — | — | US | disclosed |
| EP-4712969-A1 | CYCLIN INHIBITORS | Circle Pharma, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| US-20260062443-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMA INC (US) | 2026-03-05 | — | — | US | disclosed |
| EP-4681774-A2 | KHK INHIBITORS | Gilead Sciences, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| EP-4676476-A1 | INHIBITORS OF TDP-43 AND TAU AGGREGATION | Aquinnah Pharmaceuticals, Inc. (US) | 2026-01-14 | — | — | EP | disclosed |
| EP-0832069-A1 | BIPHENYL-2-CARBOXYLIC ACID-TETRAHYDRO-ISOQUINOLIN-6-YL AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND/OR APOLIPOPROTEIN B (Apo B) SECRETION | PFIZER INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| EP-0828754-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1998006699-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES AND THEIR PHARMACEUTICAL USE | SMITHKLINE BEECHAM PLC (GB) | 1998-02-19 | — | — | WO | disclosed |
| WO-1997043262-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS | SMITHKLINE BEECHAM P.L.C. (GB) | 1997-11-20 | — | — | WO | disclosed |
| WO-1996040640-A1 | BIPHENYL-2-CARBOXYLIC ACID-TETRAHYDRO-ISOQUINOLIN-6-YL AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND/OR APOLIPOPROTEIN B (Apo B) SECRETION | PFIZER INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996038471-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1996-12-05 | — | — | WO | disclosed |
| WO-1996035713-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER, INC. (US) | 1996-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260092059-A1 | Broad Spectrum Antiviral Compositions and Methods | IRF3, ZC3HAV1, ZC3HAV1L | PNMT 3725/4885ASIC3 4127/4885ADRA2A 3048/4885 |
| US-20260062443-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | C9, SSB, C1S | PNMT 4716/4885ASIC3 2850/4885ADRA2A 2304/4885 |
| US-20260092053-A1 | KHK INHIBITORS | KHK, SLC5A2, HK1 | PNMT 4766/4885ASIC3 2433/4885ADRA2A 1434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.