Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | SLC5A7 | Q9GZV3 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5526609 | 0.88 | SCN8A (0.49) | SCN1ASCN8A | |
| SCHEMBL5531991 | 0.87 | SCN8A (0.42) | HRH3ADRA1AKCNH2SCN1ASCN8A | |
| SCHEMBL5529852 | 0.87 | HRH3 (0.40) | HRH3EHMT2KCNH2SOS1 | |
| SCHEMBL8238217 | 0.86 | HRH3 (0.38) | HRH3EHMT2SLC5A7CYP1A2 | |
| SCHEMBL5530528 | 0.86 | HRH3 (0.41) | HRH3ADRA1AKCNH2SCN1ASCN8A | |
| SCHEMBL5528228 | 0.84 | KCNH2 (0.38) | HRH3ADRA1AKCNH2SCN1ASCN8A | |
| SCHEMBL5532960 | 0.84 | SCN8A (0.38) | HRH3ADRA1AKCNH2SCN1ASCN8A | |
| SCHEMBL8096373 | 0.82 | HRH3 (0.41) | HRH3SLC5A7CYP1A2ADRA1AKCNH2 | |
| SCHEMBL5530548 | 0.81 | SCN1A (0.39) | HRH3ADRA1AKCNH2SCN1ASCN8A | |
| SCHEMBL5532727 | 0.80 | HRH3 (0.42) | HRH3SLC5A7ADRA1ATLR9TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
| WO-2007071055-A1 | COMPOSITIONS AND METHODS FOR MODULATING GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | KCNN3, KCNN2, HCN3 | HRH3 1454/4885EHMT2 1882/4885SLC5A7 1579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.