Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5531991 | 0.91 | SCN8A (0.42) | SCN8ASCN1A | |
| SCHEMBL5529546 | 0.88 | HRH3 (0.42) | SCN8ASCN1A | |
| SCHEMBL5523125 | 0.88 | SCN8A (0.46) | SCN8ASCN1A | |
| SCHEMBL8236186 | 0.87 | SCN8A (0.46) | SCN8ASCN1A | |
| SCHEMBL5532960 | 0.87 | SCN8A (0.38) | SCN8ASCN1A | |
| SCHEMBL5528243 | 0.82 | SCN8A (0.48) | SCN8ASCN1A | |
| SCHEMBL5530528 | 0.81 | HRH3 (0.41) | SCN8ASCN1A | |
| SCHEMBL5528228 | 0.80 | KCNH2 (0.38) | SCN8ASCN1A | |
| SCHEMBL5533005 | 0.79 | TTR (0.41) | SCN8ASCN1A | |
| SCHEMBL8095793 | 0.78 | SCN8A (0.46) | SCN8ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
| WO-2007071055-A1 | COMPOSITIONS AND METHODS FOR MODULATING GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | KCNN3, KCNN2, HCN3 | SCN8A 103/4885SCN1A 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.