Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INMT | O95050 | 1/20 | 0.30 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.30 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3985599 | 0.83 | NPSR1 (0.34) | — | |
| SCHEMBL3985687 | 0.74 | CACNA1G (0.39) | INMTCACNA1GCACNA1HCACNA1I | |
| SCHEMBL8293964 | 0.60 | POLB (0.67) | — | |
| SCHEMBL9834992 | 0.60 | F2 (0.38) | INMT | |
| SCHEMBL19546254 | 0.60 | F2 (0.38) | INMT | |
| SCHEMBL867969 | 0.58 | — | — | |
| SCHEMBL13472137 | 0.58 | POLB (0.46) | — | |
| SCHEMBL17294311 | 0.58 | BRD4 (0.42) | — | |
| SCHEMBL14423078 | 0.58 | — | — | |
| SCHEMBL21011630 | 0.57 | OPRM1 (0.35) | INMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756114-B1 | HIV INTEGRASE INHIBITORS | MERCK SHARP & DOHME (US) | 2014-11-19 | — | — | EP | disclosed |
| EP-1756114-A2 | HIV INTEGRASE INHIBITORS | Merck and Co., Inc. (US) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005110414-A2 | HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 2005-11-24 | — | — | WO | disclosed |