SCHEMBL5531058

SCHEMBL5531058

Oc1ccc(-c2ccccc2)cc1C(O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.59
ESR2 Q92731 4/20 0.53
KDM4E B2RXH2 2/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
USP2 O75604 1/20 0.53
ALDH1A1 P00352 1/20 0.53
LMNA P02545 1/20 0.53
HSP90AA1 P07900 1/20 0.53
GAA P10253 1/20 0.53
MAPT P10636 1/20 0.53
HPGD P15428 1/20 0.53
ALOX15 P16050 1/20 0.53
ALOX12 P18054 1/20 0.53
HTT P42858 1/20 0.53
HSD17B10 Q99714 1/20 0.53
ACMSD Q8TDX5 3/20 0.50
HNF4A P41235 2/20 0.50
DHFR P00374 1/20 0.50
MCL1 Q07820 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51794 0.82 ALOX5 (0.57) ALOX5ESR2KDM4EMEN1KMT2A
SCHEMBL8714891 0.82 ALOX5 (0.57) ALOX5ESR2KDM4EMEN1KMT2A
SCHEMBL24638926 0.80 ALOX5 (0.55) ALOX5ESR2KDM4EMEN1KMT2A
SCHEMBL51505 0.80 ALOX5 (0.55) ALOX5ESR2KDM4EMEN1KMT2A
SCHEMBL30017397 0.79 ALOX5 (0.53) ALOX5ESR2KDM4EMEN1KMT2A
SCHEMBL2541518 0.76 PTGS2 (0.62) ALOX5ESR2KDM4EMEN1KMT2A
SCHEMBL19864010 0.76 MMP3 (0.52) ALOX5ESR2KDM4EMEN1KMT2A
SCHEMBL18381164 0.76 MMP3 (0.52) ALOX5ESR2KDM4EMEN1KMT2A
SCHEMBL4596274 0.76 ALOX5 (0.50) ALOX5ESR2KDM4EMEN1KMT2A
SCHEMBL29848221 0.75 ALOX5 (1.00) ALOX5ESR2KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070099130-A1 Developer for recording materials CHEMIPRO KASEI KAISHA, LTD. (JP) 2007-05-03 US disclosed
EP-1637337-A1 DEVELOPER FOR RECORDING MATERIALS Asahi Kasei Chemicals Corporation (JP) 2006-03-22 EP disclosed