Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | ATM | Q13315 | 3/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5574916 | 0.85 | ALDH1A1 (0.46) | AKR1C3GAAMAPTALDH1A1CDC25B | |
| SCHEMBL21063721 | 0.85 | AKR1C3 (0.55) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL4781877 | 0.84 | LTA4H (0.46) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL700595 | 0.83 | AKR1C3 (0.85) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL29447165 | 0.83 | AKR1C3 (0.85) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL28883310 | 0.80 | AKR1C3 (0.81) | AKR1C3GAAMAPTALDH1A1ATM | |
| Fluoride SCHEMBL28319246 | 0.80 | AKR1C3 (0.81) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL8022367 | 0.79 | CES2 (0.53) | MAPTATMTDP1L3MBTL1PKM | |
| SCHEMBL5375736 | 0.78 | ALDH1A1 (0.65) | AKR1C3MAPTALDH1A1ATMCDC25B | |
| SCHEMBL29163962 | 0.78 | AKR1C3 (0.77) | AKR1C3GAAMAPTALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185087-A1 | Compounds and methods for inhibiting mitotic progression | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-08-09 | — | — | US | disclosed |
| US-20050129631-A1 | Cosmetic and dermatological light protection formulations with a content of hydroxybenzophenones and alkylnaphthalates | BEIERSDORF AG (DE) | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185087-A1 | Compounds and methods for inhibiting mitotic progression | AURKC, AURKA, AURKB | AKR1C3 1731/4885GAA 2051/4885MAPT 676/4885 |
| US-20050129631-A1 | Cosmetic and dermatological light protection formulations with a content of hydroxybenzophenones and alkylnaphthalates | TYR, AHR, CYP1B1 | AKR1C3 44/4885GAA 1384/4885MAPT 2768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.