Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | PGK2 | P07205 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3736057 | 0.84 | PTPN1 (0.62) | PTPN1PTPN2PTPN6PTPN11KDM4E | |
| SCHEMBL3738148 | 0.78 | PGK1 (0.53) | PTPN1PTPRCPGK1PGK2 | |
| SCHEMBL3741701 | 0.75 | PTPN1 (0.60) | PTPN1PTPN2KDM4EF13A1PTPRC | |
| SCHEMBL1008256 | 0.70 | KDM4E (0.64) | KDM4EF13A1ESRRGALDH1A1LMNA | |
| SCHEMBL31627779 | 0.67 | MTNR1A (0.53) | LMNA | |
| SCHEMBL3737269 | 0.67 | PTPN1 (0.59) | PTPN1PTPN2ESRRG | |
| SCHEMBL10592850 | 0.66 | KDM4E (0.84) | KDM4EF13A1ALDH1A1LMNAHPGD | |
| SCHEMBL14688250 | 0.66 | HPGD (0.63) | ALDH1A1HPGD | |
| SCHEMBL3736653 | 0.66 | PTPN1 (0.76) | PTPN1PTPN2PTPRC | |
| SCHEMBL12184914 | 0.66 | ESRRG (0.67) | KDM4EF13A1ESRRGALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812012-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | Ceptyr, Inc. (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006055525-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CEPTYR, INC. (US) | 2006-05-26 | — | — | WO | disclosed |