SCHEMBL5532089

SCHEMBL5532089

COCCOCCOC(=O)NC1C(O)CC(OC=O)(OC(C)C)OC1C(O)C(O)CO

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ NANP Q8TBE9 3/20 0.35
▸ CD22 P20273 5/20 0.34
▸ SIGLEC7 Q9Y286 1/20 0.33
▸ MAG P20916 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5533916 0.92 CD22 (0.34) NANPCD22
SCHEMBL19418965 0.89 NANP (0.35) NANPCD22SIGLEC7
SCHEMBL5529701 0.86 CD22 (0.33) CD22MAG
SCHEMBL17083471 0.84 CD22 (0.32) CD22
SCHEMBL12341462 0.83 NANP (0.47) NANPCD22SIGLEC7MAG
SCHEMBL10260947 0.83 CD22 (0.35) CD22MAG
SCHEMBL5529719 0.83 CD22 (0.33) CD22
SCHEMBL17083472 0.82 CD22 (0.34) CD22
SCHEMBL17083475 0.81 CD22 (0.32) CD22
SCHEMBL5531719 0.77 CD22 (0.36) CD22SIGLEC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170136104-A1 GLYCOPEGYLATED FACTOR IX NOVO NORDISK AS (DK) 2017-05-18 — — US disclosed
US-20160361427-A1 Glycopegylated Factor IX NOVO NORDISK AS (DK) 2016-12-15 — — US disclosed
US-20160184412-A1 Glycopegylated Factor IX NOVO NORDISK AS (DK) 2016-06-30 — — US disclosed
US-20160158319-A1 REMODELING AND GLYCOPEGYLATION OF FIBROBLAST GROWTH FACTOR (FGF) NOVO NORDISK A/S (DK) 2016-06-09 — — US disclosed
US-9200049-B2 Remodeling and glycopegylation of fibroblast growth factor (FGF) NOVO NORDISK A/S (DK) 2015-12-01 — — US disclosed
US-20150258206-A1 GLYCEROL LINKED PEGYLATED SUGARS AND GLYCOPEPTIDES NOVO NORDISK AS (DK) 2015-09-17 — — US disclosed
US-20150125437-A1 Glycopegylated Factor IX NOVO NORDISK AS (DK) 2015-05-07 — — US disclosed
US-8916360-B2 Glycopegylated erythropoietin NOVO NORDISK A/S (DK) 2014-12-23 — — US disclosed
US-8791066-B2 Branched PEG remodeling and glycosylation of glucagon-like peptide-1 [GLP-1] NOVO NORDISK A/S (DK) 2014-07-29 — — US disclosed
US-8791070-B2 Glycopegylated factor IX NOVO NORDISK A/S (DK) 2014-07-29 — — US disclosed
US-20140112903-A1 Glycopegylated Factor IX NOVO NORDISK A/S (DK) 2014-04-24 — — US disclosed
US-8633157-B2 Glycopegylated erythropoietin NOVO NORDISK A/S (DK) 2014-01-21 — — US disclosed
US-8632770-B2 Glycopegylated factor IX NOVO NORDISK A/S (DK) 2014-01-21 — — US disclosed
US-20130137157-A1 GLYCOPEGYLATED FACTOR VII AND FACTOR VIIA NOVO NORDISK A/S (DK) 2013-05-30 — — US disclosed
US-20130059780-A1 BRANCHED PEG REMODELING AND GLYCOSYLATION OF GLUCAGON-LIKE PEPTIDE-1 [GLP-1] BIOGENERIX AG (DE) 2013-03-07 — — US disclosed
US-20120172300-A1 REMODELING AND GLYCOPEGYLATION OF FIBROBLAST GROWTH FACTOR (FGF) NOVO NORDISK A/S (DK) 2012-07-05 — — US disclosed
US-20120107867-A1 GLYCOPEGYLATED ERYTHROPOIETIN NOVO NORDISK A/S (DK) 2012-05-03 — — US disclosed
US-20110318780-A1 ENZYMATIC MODIFICATION OF GLYCOPEPTIDES BIOGENERIX AG (DE) 2011-12-29 — — US disclosed
US-20110003744-A1 Glycopegylated Erythropoietin Formulations NOVO NORDISK A/S (DK) 2011-01-06 — — US disclosed
US-20100330060-A1 GLYCOPEGYLATED FACTOR IX NOVO NORDISK A/S (DK) 2010-12-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130059780-A1 BRANCHED PEG REMODELING AND GLYCOSYLATION OF GLUCAGON-LIKE PEPTIDE-1 [GLP-1] GLP1R, GIPR, IAPP NANP 866/4885CD22 407/4885SIGLEC7 96/4885
US-20160158319-A1 REMODELING AND GLYCOPEGYLATION OF FIBROBLAST GROWTH FACTOR (FGF) FGF2, FGF1, FGFR1 NANP 163/4885CD22 392/4885SIGLEC7 205/4885
US-20120172300-A1 REMODELING AND GLYCOPEGYLATION OF FIBROBLAST GROWTH FACTOR (FGF) FGF2, FGF1, FGFR1 NANP 163/4885CD22 392/4885SIGLEC7 205/4885
US-20100330060-A1 GLYCOPEGYLATED FACTOR IX F9, F13A1, F13B NANP 160/4885CD22 382/4885SIGLEC7 43/4885
US-20160361427-A1 Glycopegylated Factor IX F9, F13A1, F13B NANP 175/4885CD22 514/4885SIGLEC7 53/4885
US-20170136104-A1 GLYCOPEGYLATED FACTOR IX F9, F13A1, F13B NANP 175/4885CD22 514/4885SIGLEC7 53/4885
US-20110003744-A1 Glycopegylated Erythropoietin Formulations EPOR, UGGT1, GNE NANP 838/4885CD22 375/4885SIGLEC7 96/4885
US-20160184412-A1 Glycopegylated Factor IX F9, F13A1, F13B NANP 172/4885CD22 501/4885SIGLEC7 53/4885
US-20150125437-A1 Glycopegylated Factor IX F9, F13A1, F13B NANP 175/4885CD22 514/4885SIGLEC7 53/4885
US-20150258206-A1 GLYCEROL LINKED PEGYLATED SUGARS AND GLYCOPEPTIDES UGCG, B3GAT3, UGGT1 NANP 306/4885CD22 367/4885SIGLEC7 16/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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