Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30960095 | 0.87 | CA1 (0.40) | CA1CA2CA9 | |
| Hydrogen Peroxide SCHEMBL9436488 | 0.87 | CA1 (0.40) | CA1CA2CA9 | |
| SCHEMBL30514 | 0.87 | — | — | |
| SCHEMBL28408897 | 0.84 | — | — | |
| SCHEMBL4235388 | 0.82 | CA1 (0.36) | CA1CA2CA9 | |
| Ammonia Solution, Strong SCHEMBL1160872 | 0.82 | CA1 (0.36) | CA1CA2CA9 | |
| SCHEMBL4876131 | 0.82 | — | — | |
| SCHEMBL1155717 | 0.82 | CA1 (0.36) | CA1CA2CA9 | |
| SCHEMBL7749080 | 0.82 | — | — | |
| Bicarbonate SCHEMBL11048608 | 0.82 | CA1 (0.50) | CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123491-A1 | Podophyllotoxin derivatives as igf-1r inhibitors | BIOVITRUM AB (SE) | 2007-05-31 | — | — | US | disclosed |
| EP-1615932-A2 | PODOPHHYLLOTOXIN DERIVATIVES AS IGF-1R INHIBITORS | Biovitrum AB (SE) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004093781-A2 | PODOPHYLLOTOXIN DERIVATIVES AS IGF-1R INHIBITORS | BIOVITRUM AB (SE) | 2004-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123491-A1 | Podophyllotoxin derivatives as igf-1r inhibitors | IGF1R, IGFBP1, INSR | CA1 4699/4885CA2 4421/4885CA9 3925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.