Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 9/20 | 0.41 |
| ▸ | PRKACA | P17612 | 2/20 | 0.40 |
| ▸ | CDK8 | P49336 | 2/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27549719 | 0.81 | HPGD (0.40) | KDM4EALDH1A1MAPTTDP1KDR | |
| SCHEMBL5192672 | 0.77 | ESR1 (0.49) | ESR1CHEK1LIMK1MAPK14KDM4E | |
| SCHEMBL18419722 | 0.74 | ESR1 (0.46) | ESR1CHEK1LIMK1MAPK14KDM4E | |
| SCHEMBL1263722 | 0.74 | ESR1 (0.50) | ESR1CHEK1LIMK1MAPK14KDM4E | |
| SCHEMBL4482636 | 0.74 | ESR1 (0.46) | ESR1CHEK1LIMK1MAPK14KDM4E | |
| SCHEMBL786747 | 0.74 | HDAC4 (0.52) | ESR1CHEK1LIMK1MAPK14KDM4E | |
| SCHEMBL19065614 | 0.74 | ESR1 (0.46) | ESR1CHEK1LIMK1MAPK14KDM4E | |
| SCHEMBL6440778 | 0.74 | KMT2A (0.50) | ESR1CHEK1LIMK1MAPK14KDM4E | |
| SCHEMBL5533567 | 0.74 | ESR1 (0.46) | ESR1CHEK1LIMK1MAPK14KDM4E | |
| SCHEMBL28038136 | 0.74 | ESR1 (0.46) | ESR1CHEK1LIMK1MAPK14KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | claimed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | claimed |
| CN-107921144-B | Aureostatin analogs and conjugate conjugates thereof with cell-binding molecules | 杭州多禧生物科技有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-116726190-A | Aureostatin analogs and conjugate conjugates thereof with cell-binding molecules | 杭州多禧生物科技有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-107921144-A | Auristatin analogs and conjugates thereof with cell-binding molecules | 杭州多禧生物科技有限公司 | 2018-04-17 | — | — | CN | disclosed |
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
| US-6514988-B1 | A pregnancy controlling agent and a menstrual cycle controlling agent; useful as an agent of spawning promotion in fish | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-02-04 | — | — | US | disclosed |
| US-6187788-B1 | THIENO(2,3-B)(DIHYDRO)PYRIDINE DERIVATIVES; GONADOTROPIN-RELEASING HORMONE ANTAGONISTS; ANTICARCINOGENIC AGENTS; SEXUAL AND UROGENITAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| US-6180792-B1 | DRUGS, ANTISECRETORY AGENTS AND HORMONE INHIBITORS FOR LH-RH | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | ESR1 4728/4885CHEK1 3421/4885LIMK1 2788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.