Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.60 |
| ▸ | CASP2 | P42575 | 1/20 | 0.58 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | NAAA | Q02083 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5524009 | 1.00 | FAAH (0.60) | FAAHCASP2DNM1TP53SMN1; SMN2 | |
| SCHEMBL10723379 | 1.00 | FAAH (0.60) | FAAHCASP2DNM1TP53SMN1; SMN2 | |
| SCHEMBL5538333 | 1.00 | FAAH (0.60) | FAAHCASP2DNM1TP53SMN1; SMN2 | |
| SCHEMBL5531859 | 1.00 | FAAH (0.60) | FAAHCASP2DNM1TP53SMN1; SMN2 | |
| SCHEMBL10722577 | 0.98 | TP53 (0.58) | FAAHCASP2DNM1TP53SMN1; SMN2 | |
| SCHEMBL8437935 | 0.95 | FAAH (0.55) | FAAHCASP2DNM1TP53SMN1; SMN2 | |
| SCHEMBL8440020 | 0.94 | NAAA (0.57) | FAAHCASP2DNM1TP53SMN1; SMN2 | |
| SCHEMBL8437643 | 0.94 | NAAA (0.57) | FAAHCASP2DNM1TP53SMN1; SMN2 | |
| SCHEMBL5139456 | 0.91 | EPHX2 (0.66) | EPHX2SLC6A5 | |
| SCHEMBL5139457 | 0.91 | EPHX2 (0.66) | EPHX2SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513538-A4 | NOVEL METHODS FOR THE DELIVERY OF POLYNUCLEOTIDES TO CELLS | MIRUS BIO CORP (US) | 2007-08-22 | — | — | EP | disclosed |
| EP-1513538-A2 | NOVEL METHODS FOR THE DELIVERY OF POLYNUCLEOTIDES TO CELLS | Mirus Corporation (US) | 2005-03-16 | — | — | EP | disclosed |
| US-20030235916-A1 | Novel methods for the delivery of polynucleotides to cells | ROCHE MADISON INC. | 2003-12-25 | — | — | US | disclosed |
| WO-2003106636-A2 | NOVEL METHODS FOR THE DELIVERY OF POLYNUCLEOTIDES TO CELLS | MIRUS CORPORATION (US) | 2003-12-24 | — | — | WO | disclosed |