Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.57 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.55 |
| ▸ | FAAH | O00519 | 4/20 | 0.54 |
| ▸ | CASP2 | P42575 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | SELP | P16109 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440020 | 1.00 | NAAA (0.57) | NAAADNM1FAAHCASP2TP53 | |
| SCHEMBL10723379 | 0.94 | FAAH (0.60) | NAAADNM1FAAHCASP2TP53 | |
| SCHEMBL5524009 | 0.94 | FAAH (0.60) | NAAADNM1FAAHCASP2TP53 | |
| SCHEMBL5531859 | 0.94 | FAAH (0.60) | NAAADNM1FAAHCASP2TP53 | |
| SCHEMBL5538333 | 0.94 | FAAH (0.60) | NAAADNM1FAAHCASP2TP53 | |
| SCHEMBL5533634 | 0.94 | FAAH (0.60) | NAAADNM1FAAHCASP2TP53 | |
| SCHEMBL10722577 | 0.92 | TP53 (0.58) | NAAADNM1FAAHCASP2TP53 | |
| SCHEMBL8437935 | 0.90 | FAAH (0.55) | NAAADNM1FAAHCASP2TP53 | |
| SCHEMBL5139456 | 0.86 | EPHX2 (0.66) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| SCHEMBL5139457 | 0.86 | EPHX2 (0.66) | CNR1ALDH1A1HPGDTRPV1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757560-B1 | OPHTHALMIC COMPOSITIONS COMPRISING AMIDOAMINES | ALCON LAB INC (US) | 1999-12-22 | — | — | EP | disclosed |
| EP-0757560-A1 | USE OF AMIDOAMINES IN OPHTHALMIC COMPOSITIONS | ALCON LABORATORIES, INC. (US) | 1997-02-12 | — | — | EP | disclosed |
| US-5573726-A | DISINFECTING CONTACT LENSES | ALCON LABORATORIES, INC. (US) | 1996-11-12 | — | — | US | disclosed |
| WO-1996026747-A2 | USE OF AMIDOAMINES IN OPHTHALMIC COMPOSITIONS | ALCON LABORATORIES, INC. (US) | 1996-09-06 | — | — | WO | disclosed |