Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30749067 | 0.78 | CYP2D6 (0.44) | ALDH1A1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL5710315 | 0.77 | CYP2D6 (0.31) | TSHR | |
| SCHEMBL6907341 | 0.74 | KCNMA1 (0.35) | ALDH1A1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL30748986 | 0.70 | CHRM5 (0.43) | ALDH1A1CREBBPSMN1; SMN2NPSR1MAPT | |
| SCHEMBL11510699 | 0.69 | ALDH1A1 (0.36) | ALDH1A1CREBBPL3MBTL1MEN1KMT2A | |
| SCHEMBL2243707 | 0.68 | NPSR1 (0.44) | ALDH1A1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL5534845 | 0.67 | HDAC8 (0.32) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1554369 | 0.67 | MAPT (0.39) | ALDH1A1L3MBTL1LMNAKCNMA1KMT2A | |
| SCHEMBL12888687 | 0.65 | CYP2D6 (0.34) | ALDH1A1HTTTSHR | |
| SCHEMBL1826432 | 0.65 | MEN1 (0.39) | ALDH1A1L3MBTL1LMNAHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070208037-A1 | FUNGICIDAL 5-PHENYL SUBSTITUTED 2-(CYANOAMINO) PYRIMIDINES | PEES KLAUS-JUERGEN | 2007-09-06 | — | — | US | disclosed |
| US-7230104-B2 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-12 | — | — | US | disclosed |
| US-20050282828-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | PEES KLAUS-JUERGEN | 2005-12-22 | — | — | US | disclosed |
| US-20050282847-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | PEES KLAUS-JUERGEN | 2005-12-22 | — | — | US | disclosed |
| EP-1577312-A1 | Triazolopyrimidine intermediate compounds for fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2005-09-21 | — | — | EP | disclosed |
| US-6943252-B2 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2005-09-13 | — | — | US | disclosed |
| EP-1289963-B1 | FUNGICIDAL 5-PHENYL SUBSTITUTED 2-(CYANOAMINO) PYRIMIDINES | BASF AG (DE) | 2005-08-31 | — | — | EP | disclosed |
| US-20040147744-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | PEES KLAUS-JUERGEN | 2004-07-29 | — | — | US | disclosed |
| US-6632821-B2 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2003-10-14 | — | — | US | disclosed |
| US-20030088096-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | BASF AKTIENGESELLSCHAFT | 2003-05-08 | — | — | US | disclosed |
| EP-1289963-A1 | FUNGICIDAL 5-PHENYL SUBSTITUTED 2-(CYANOAMINO) PYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096314-A1 | FUNGICIDAL 5-PHENYL SUBSTITUTED 2-(CYANOAMINO) PYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2001-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147744-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | CBR3, CBR1, NOX5 | ALDH1A1 563/4885CREBBP 4825/4885L3MBTL1 227/4885 |
| US-20050282828-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | CBR3, CBR1, CYP3A5 | ALDH1A1 1325/4885CREBBP 4838/4885L3MBTL1 168/4885 |
| US-20070208037-A1 | FUNGICIDAL 5-PHENYL SUBSTITUTED 2-(CYANOAMINO) PYRIMIDINES | CBR3, NOX5, CBR1 | ALDH1A1 1311/4885CREBBP 4836/4885L3MBTL1 200/4885 |
| US-20030088096-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | CBR1, CBR3, ARSA | ALDH1A1 622/4885CREBBP 4662/4885L3MBTL1 238/4885 |
| US-20050282847-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | CBR3, NOX5, CBR1 | ALDH1A1 1319/4885CREBBP 4825/4885L3MBTL1 232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.