Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | PLAT | P00750 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.45 |
| ▸ | ITGA2 | P17301 | 2/20 | 0.45 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6665956 | 0.85 | RXFP1 (0.41) | PLAUMEN1KMT2A | |
| SCHEMBL2804700 | 0.81 | MEN1 (0.58) | MELKF2PLGPLAUPLAT | |
| SCHEMBL8208303 | 0.79 | APOB (0.62) | MELKASIC3SLC2A1MEN1KMT2A | |
| SCHEMBL9092238 | 0.77 | MEN1 (0.44) | ITGB3ITGA2BMEN1KMT2AATM | |
| SCHEMBL8197860 | 0.75 | MELK (0.68) | MELKF2PLGPLAUPLAT | |
| SCHEMBL31423364 | 0.74 | MELK (0.55) | MELKITGB3ITGA2SLC2A1ITGA2B | |
| SCHEMBL8509528 | 0.74 | PRMT5 (0.43) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31423385 | 0.73 | SLC2A1 (0.55) | MELKITGB3ITGA2SLC2A1ITGA2B | |
| SCHEMBL8025148 | 0.73 | APOB (0.48) | MELKASIC3SLC2A1PTK2 | |
| SCHEMBL6717457 | 0.72 | MELK (0.52) | MELKITGB3ITGA2SLC2A1ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806149-A1 | SOLID MEDICINAL PREPARATION IMPROVED IN SOLUBILITY AND STABILITY AND PROCESS FOR PRODUCING THE SAME | Japan Tobacco, Inc. (JP) | 2007-07-11 | — | — | EP | disclosed |