SCHEMBL5535205

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5546366	0.85	LMNA (0.39)	LMNAUGT2B7TRPA1PTGS1CACNA1C
	SCHEMBL9202166	0.82	ALDH1A1 (0.40)	ALDH1A1GAASMN1; SMN2NPC1RAB9A
	SCHEMBL510807	0.71	CYP2A6 (0.44)	LMNAALDH1A1GAASMN1; SMN2NPC1
	SCHEMBL1204761	0.69	CYP2A6 (0.43)	ALDH1A1HTTNPC1RAB9AKDM4E
	SCHEMBL16290161	0.69	CYP1A2 (0.43)	LMNAALDH1A1HIF1ACA1CA2
	SCHEMBL4477922	0.69	CYP2A6 (0.50)	LMNAALDH1A1SMN1; SMN2NPC1RAB9A
	SCHEMBL7746357	0.69	UGT2B7 (0.41)	LMNAUGT2B7TRPA1PTGS1CACNA1C
	SCHEMBL30031337	0.69	UGT2B7 (0.58)	LMNAUGT2B7TRPA1PTGS1CACNA1C
	SCHEMBL4832080	0.69	UGT2B7 (0.52)	LMNAUGT2B7TRPA1PTGS1CACNA1C
	SCHEMBL181347	0.69	UGT2B7 (0.58)	LMNAUGT2B7TRPA1PTGS1CACNA1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.