Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5535205 | 0.82 | LMNA (0.39) | ALDH1A1GAAHPGDALOX15HSD17B10 | |
| SCHEMBL9167387 | 0.73 | ALDH1A1 (0.53) | ALDH1A1GAAHPGDUSP2PKM | |
| SCHEMBL16684715 | 0.71 | UGT2B7 (0.59) | ALDH1A1GAAHPGDUSP2PKM | |
| SCHEMBL5401290 | 0.71 | UGT2B7 (0.59) | ALDH1A1GAAHPGDUSP2PKM | |
| SCHEMBL3725681 | 0.70 | ALDH1A1 (0.50) | ALDH1A1GAAHPGDUSP2PKM | |
| SCHEMBL3727201 | 0.70 | ALDH1A1 (0.50) | ALDH1A1GAAHPGDUSP2PKM | |
| SCHEMBL2491242 | 0.69 | UGT2B7 (0.52) | ALDH1A1GAAHPGDUSP2PKM | |
| SCHEMBL5546366 | 0.68 | LMNA (0.39) | ALDH1A1GAAHPGDALOX15HSD17B10 | |
| SCHEMBL20309118 | 0.68 | ALDH1A1 (0.53) | ALDH1A1ALOX15HSD17B10NPC1RAB9A | |
| SCHEMBL29473917 | 0.68 | ALDH1A1 (0.53) | ALDH1A1ALOX15HSD17B10NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463969-B1 | New compounds of 4-aminobutyric acid, process for their preparation and pharmaceutical preparations containing them | ADIR (FR) | 1995-02-08 | — | — | EP | disclosed |
| EP-0463969-A1 | New compounds of 4-aminobutyric acid, process for their preparation and pharmaceutical preparations containing them | ADIR ET COMPAGNIE (FR) | 1992-01-02 | — | — | EP | disclosed |