Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ASF1A | Q9Y294 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15741867 | 0.87 | RAB9A (0.65) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL23062734 | 0.80 | RAB9A (0.79) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL13906018 | 0.80 | RAB9A (0.79) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL1025210 | 0.75 | AGTR1 (0.46) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL13826730 | 0.70 | NPC1 (0.68) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL14517019 | 0.70 | RAB9A (0.71) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL6490600 | 0.69 | TUBB4A (0.63) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL4801570 | 0.69 | TUBB4A (0.63) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL8939918 | 0.68 | RAB9A (0.74) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL28631970 | 0.68 | NPC1 (0.69) | RAB9ANPC1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608623-A4 | METAL ION CHELATORS AND THERAPEUTIC USE THEREOF | NEWSOUTH INNOVATIONS PTY LTD (AU) | 2007-07-18 | — | — | EP | disclosed |
| EP-1608623-A1 | METAL ION CHELATORS AND THERAPEUTIC USE THEREOF | UNISEARCH LIMITED (AU) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004069801-A1 | METAL ION CHELATORS AND THERAPEUTIC USE THEREOF | UNISEARCH LIMITED (AU) | 2004-08-19 | — | — | WO | disclosed |