SCHEMBL12660985

SCHEMBL12660985

O=c1c2c3c(=O)n(-c4ccc(F)cc4)c(=O)c3c3c(=O)n(-c4ccc(F)cc4)c(=O)c3c2c(=O)n1-c1ccc(F)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.48
GSK3A P49840 1/20 0.47
GSK3B P49841 1/20 0.47
MPI P34949 3/20 0.44
PMM2 O15305 2/20 0.44
APOBEC3G Q9HC16 2/20 0.44
METAP2 P50579 1/20 0.44
G6PD P11413 1/20 0.44
KDM4E B2RXH2 1/20 0.43
TSHR P16473 1/20 0.43
HTT P42858 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.42
HKDC1 Q2TB90 3/20 0.42
HPGD P15428 1/20 0.42
POLB P06746 1/20 0.41
RAB9A P51151 1/20 0.40
PHOSPHO1 Q8TCT1 1/20 0.40
NOTUM Q6P988 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5535503 0.81 CA12 (0.55) MGLLGSK3AGSK3BMPIPMM2
SCHEMBL17537368 0.79 GSK3A (0.55) MGLLGSK3AGSK3BMPIPMM2
SCHEMBL12660977 0.74 MAPK1 (0.65) MGLLGSK3AGSK3BMPIPMM2
SCHEMBL23643021 0.73 GSK3A (0.60) MGLLGSK3AGSK3BMPIPMM2
SCHEMBL3021600 0.73 GSK3A (0.60) MGLLGSK3AGSK3BMETAP2KDM4E
SCHEMBL12660980 0.73 FAAH (0.55) MGLLMPIPMM2APOBEC3GMETAP2
SCHEMBL5535430 0.73 KDM4E (0.49) MGLLGSK3AGSK3BKDM4EHTT
SCHEMBL25095011 0.72 HPGD (0.47) MGLLGSK3AGSK3BMPIPMM2
SCHEMBL8208644 0.71 MAPK1 (0.56) MGLLGSK3AGSK3BMPIPMM2
SCHEMBL19276488 0.69 GSK3A (0.47) MGLLGSK3AGSK3BMETAP2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337445-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING DEVICE SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2023-10-19 US disclosed
US-20230337445-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING DEVICE SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2023-10-19 US disclosed
US-8847367-B2 Organic electroluminescent device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2014-09-30 US disclosed
US-8847367-B2 Organic electroluminescent device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2014-09-30 US disclosed
US-20110101319-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL CO., LTD. (JP) 2011-05-05 US disclosed
US-20110101319-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL CO., LTD. (JP) 2011-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110101319-A1 ORGANIC ELECTROLUMINESCENT DEVICE SLCO4C1, SLCO2A1, SLCO2B1 MGLL 2177/4885GSK3A 3132/4885GSK3B 3363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.