Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amylene Hydrate SCHEMBL28185800 | 0.82 | CA5A (0.44) | CA5ACA5BTSHRALDH1A1TDP1 | |
| Nitric Acid SCHEMBL441121 | 0.80 | CA5A (0.42) | CA5ACA5BTSHRALDH1A1 | |
| Nitric Acid SCHEMBL1587834 | 0.79 | — | — | |
| Nitric Acid SCHEMBL2217977 | 0.79 | CA5A (0.67) | CA5ACA5BTSHRALDH1A1LMNA | |
| Nitric Acid SCHEMBL2217867 | 0.79 | CA5A (0.67) | CA5ACA5BTSHRALDH1A1LMNA | |
| Nitric Acid SCHEMBL10611129 | 0.79 | CA5A (0.47) | CA5ACA5BTSHRALDH1A1LMNA | |
| Nitric Acid SCHEMBL10592576 | 0.78 | CA5A (0.40) | CA5ACA5BTSHRALDH1A1 | |
| Nitric Acid SCHEMBL14860317 | 0.77 | CA5A (0.44) | CA5ACA5BTSHRALDH1A1 | |
| Nitric Acid SCHEMBL11333785 | 0.77 | CA5A (0.44) | CA5ACA5BTSHRALDH1A1TDP1 | |
| Nitric Acid SCHEMBL31295856 | 0.76 | ALDH1A1 (0.42) | CA5ACA5BTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-210473886-U | Preparation system of trimethylolethane trinitrate reaction acid | 宜宾北方川安化工有限公司 | 2020-05-08 | — | — | CN | disclosed |
| WO-2007100910-A2 | TRANSDERMAL PATCHES CONTAINING A NITRIC OXIDE-DONOR AND A SECOND ACTIVE AGENT AND ASSOCIATED METHODS | CURE THERAPEUTICS, INC. (US) | 2007-09-07 | — | — | WO | disclosed |
| WO-2007092284-A2 | LOW DOSE NO DONOR-CONTAINING TRANSDERMAL PATCH | CURE THERAPEUCTICS, INC. (US) | 2007-08-16 | — | — | WO | disclosed |
| WO-2000043012-A1 | CONTROLLING HEART RATE OR BLOOD PRESSURE IN PATIENTS CO-MEDICATED WITH PHOSPHODIESTERASE INHIBITORS FOR TREATMENT OF IMPOTENCE | SELECTUS PHARMACEUTICALS, INC. (US) | 2000-07-27 | — | — | WO | disclosed |