SCHEMBL5536229

SCHEMBL5536229

[c]1cccc(N(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
MAPT P10636 2/20 0.44
KDM4E B2RXH2 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
CRHBP P24387 1/20 0.38
ATM Q13315 1/20 0.38
CRHR2 Q13324 1/20 0.38
TLR9 Q9NR96 1/20 0.38
NPSR1 Q6W5P4 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 3/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28643699 0.84 ACHE (0.35) ALDH1A1L3MBTL1TDP1MAPTKDM4E
SCHEMBL27718244 0.83 ALDH1A1 (0.38) ALDH1A1L3MBTL1TDP1MAPTKDM4E
Water SCHEMBL10781474 0.79 ALDH1A1 (0.63) ALDH1A1L3MBTL1TDP1MAPTKDM4E
Water SCHEMBL28042967 0.79 ALDH1A1 (0.63) ALDH1A1L3MBTL1TDP1MAPTKDM4E
SCHEMBL1378606 0.78 ALDH1A1 (0.46) ALDH1A1L3MBTL1TDP1MAPTKDM4E
SCHEMBL295902 0.78 ALDH1A1 (0.46) ALDH1A1L3MBTL1TDP1MAPTKDM4E
SCHEMBL698362 0.77 LMNA (0.40) ALDH1A1TDP1MAPTMEN1KMT2A
SCHEMBL128447 0.77 ALDH1A1 (0.50) ALDH1A1L3MBTL1TDP1MAPTKDM4E
SCHEMBL30959 0.76 ALDH1A1 (0.67) ALDH1A1L3MBTL1TDP1MAPTKDM4E
SCHEMBL9490577 0.76 ALDH1A1 (0.67) ALDH1A1L3MBTL1TDP1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344695-A Hydroxyl-enriched cycloolefin copolymer long afterglow material and application thereof 重庆理工大学 2024-07-16 CN claimed
CN-107141391-B Ethylene-polar styrene quasi-random copolymer and preparation method thereof 中国科学院长春应用化学研究所 2020-03-13 CN claimed
CN-110028506-A The red orange photo-thermal excitation delayed fluorescence material of two pyrido phenazinyl, synthetic method and its application 黑龙江大学 2019-07-19 CN claimed
US-6509426-B2 Dichloro(1,1'-dimethylsilylenebis(2-methyl-4-(4-methoxyphenyl) -4H-azulenyl))zirconium, for example; can produce polyolefin with high molecular weight and high melting point for extrusion or injection moldability JAPAN POLYCHEM CORPORATION (JP) 2003-01-21 US claimed
CN-118344695-A Hydroxyl-enriched cycloolefin copolymer long afterglow material and application thereof 重庆理工大学 2024-07-16 CN disclosed
CN-117616032-A Rare earth complex 东曹株式会社 2024-02-27 CN disclosed
US-20240057370-A1 LIGHT EMITTING ELEMENT, METHOD FOR MANUFACTURING THE SAME, AND DISPLAY DEVICE SONY GROUP CORP (JP) 2024-02-15 US disclosed
US-11818906-B2 Display device with reduced reflection Sony Group Corporation (JP) 2023-11-14 US disclosed
US-11765923-B2 Light emitting element, method for manufacturing the same, and display device Sony Group Corporation (JP) 2023-09-19 US disclosed
CN-115260057-B Improved method for preparing functionalized cis-trans dicyanoethylene compound through desulfurization of 2, 5-dinitrothiophene 中国科学院大学 2023-07-25 CN disclosed
CN-116445150-A Aromatic amine compound containing oxadiazole and preparation method and application thereof 中国科学院福建物质结构研究所 2023-07-18 CN disclosed
CN-115260057-A Improved method for preparing functionalized cis-trans dicyanoethylene compound by 2,5-dinitrothiophene desulfurization 中国科学院大学 2022-11-01 CN disclosed
EP-2570418-A2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-03-20 EP disclosed
EP-1555267-B1 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES OTSUKA PHARMA CO LTD (JP) 2013-01-16 EP disclosed
US-20120322334-A1 METHOD OF MANUFACTURING FILM AND METHOD OF MANUFACTURING DISPLAY SONY CORPORATION (JP) 2012-12-20 US disclosed
CN-101258221-A Light-emitting device material and light-emitting device TORAY INDUSTRIES (JP) 2008-09-03 CN disclosed
US-7262212-B2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-08-28 US disclosed
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-05-04 US disclosed
CN-1705670-A 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds OTSUKA PHARMA CO LTD (JP) 2005-12-07 CN disclosed
EP-1555267-A1 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-07-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles NR2C2, NR4A3, NR4A2 ALDH1A1 355/4885L3MBTL1 1931/4885TDP1 4666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.