Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | FAAH | O00519 | 1/20 | 0.60 |
| ▸ | MDH1 | P40925 | 1/20 | 0.57 |
| ▸ | MDH2 | P40926 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | PRKAB2 | O43741 | 4/20 | 0.56 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.56 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.56 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.56 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.56 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.56 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.53 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.52 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5536935 | 0.89 | L3MBTL1 (0.67) | L3MBTL1SIGMAR1FAAHMDH1MDH2 | |
| SCHEMBL5544743 | 0.87 | L3MBTL1 (0.64) | L3MBTL1SIGMAR1FAAHMDH1MDH2 | |
| SCHEMBL14438076 | 0.86 | L3MBTL1 (0.74) | L3MBTL1SIGMAR1FAAHMDH1MDH2 | |
| SCHEMBL5537938 | 0.85 | L3MBTL1 (0.65) | L3MBTL1SIGMAR1FAAHMDH1MDH2 | |
| SCHEMBL5543050 | 0.84 | L3MBTL1 (0.61) | L3MBTL1SIGMAR1FAAHMDH1MDH2 | |
| SCHEMBL27629355 | 0.84 | SIGMAR1 (0.68) | L3MBTL1SIGMAR1FAAHKDM4EALDH1A1 | |
| SCHEMBL5547583 | 0.84 | L3MBTL1 (0.67) | L3MBTL1SIGMAR1FAAHMDH1MDH2 | |
| SCHEMBL5537942 | 0.82 | RORC (0.71) | L3MBTL1SIGMAR1FAAHMDH1MDH2 | |
| SCHEMBL17955280 | 0.81 | HPGD (0.72) | L3MBTL1SIGMAR1FAAHKDM4EALDH1A1 | |
| SCHEMBL27282763 | 0.80 | L3MBTL1 (0.74) | L3MBTL1SIGMAR1FAAHMDH1MDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | L3MBTL1 1931/4885SIGMAR1 234/4885FAAH 4363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.