Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | CETP | P11597 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78300 | 0.86 | CETP (0.73) | CETPLMNAMEN1KMT2ATSHR | |
| SCHEMBL10703263 | 0.86 | CETP (0.73) | CETPLMNAMEN1KMT2ATSHR | |
| SCHEMBL5542638 | 0.85 | ALDH1A1 (0.53) | MAPK1CETPGAAALDH1A1MAPT | |
| SCHEMBL29315244 | 0.81 | MAPK1 (1.00) | MAPK1HTTCETPGAAALDH1A1 | |
| SCHEMBL7750852 | 0.81 | HDAC3 (0.71) | MAPK1HTTGAAALDH1A1MAPT | |
| SCHEMBL29721986 | 0.81 | MAPK1 (0.69) | MAPK1HTTCETPGAAALDH1A1 | |
| SCHEMBL5536448 | 0.81 | MAPK1 (0.69) | MAPK1HTTCETPGAAALDH1A1 | |
| SCHEMBL6658490 | 0.81 | MAPK1 (0.69) | MAPK1HTTGAAALDH1A1MAPT | |
| SCHEMBL9850229 | 0.81 | CYP2C19 (0.62) | MAPK1GAAMAPTMEN1KMT2A | |
| SCHEMBL12284937 | 0.81 | ALDH1A1 (0.69) | MAPK1HTTCETPGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| US-6989439-B2 | Color developing agent, azo dye, silver halide photographic light-sensitive material, and image-forming method | FUJI PHOTO FILM CO., LTD. (JP) | 2006-01-24 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-20030204094-A1 | Color developing agent, azo dye, silver halide photographic light-sensitive material, and image-forming method | FUJI PHOTO FILM CO., LTD. | 2003-10-30 | — | — | US | disclosed |
| US-6555691-B2 | Absorption characteristics, and which is high in fastness to light, heat, humidity, air, chemicals | FUJI PHOTO FILM CO., LTD. (JP) | 2003-04-29 | — | — | US | disclosed |
| US-20020146651-A1 | Color developing agent, azo dye, silver halide photographic light-sensitive material, and image-forming method | FUJIFILM CORPORATION (JP) | 2002-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030204094-A1 | Color developing agent, azo dye, silver halide photographic light-sensitive material, and image-forming method | IK, AIPL1, CRY1 | MAPK1 913/4885HTT 1411/4885CETP 2451/4885 |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | MAPK1 1392/4885HTT 4644/4885CETP 4769/4885 |
| US-20020146651-A1 | Color developing agent, azo dye, silver halide photographic light-sensitive material, and image-forming method | IK, AIPL1, CRY1 | MAPK1 913/4885HTT 1411/4885CETP 2451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.