Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16294121 | 0.83 | GLA (0.42) | KDM4ETDP1ALDH1A1MEN1USP2 | |
| SCHEMBL17700618 | 0.83 | GLA (0.42) | KDM4ETDP1ALDH1A1MEN1USP2 | |
| SCHEMBL16306959 | 0.83 | GLA (0.42) | KDM4ETDP1ALDH1A1MEN1USP2 | |
| SCHEMBL16960018 | 0.81 | KDM4E (0.39) | KDM4ETDP1ALDH1A1MEN1USP2 | |
| SCHEMBL2061830 | 0.80 | GAA (0.41) | KDM4ETDP1ALDH1A1MEN1USP2 | |
| SCHEMBL27885171 | 0.78 | LMNA (0.42) | KDM4ETDP1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL12363071 | 0.78 | LMNA (0.38) | KDM4ETDP1ALDH1A1MEN1USP2 | |
| SCHEMBL7426724 | 0.77 | ADRA2A (0.45) | KDM4ETDP1ALDH1A1MEN1BLM | |
| SCHEMBL3988110 | 0.77 | ADRA2A (0.45) | KDM4ETDP1ALDH1A1MEN1BLM | |
| SCHEMBL82671 | 0.76 | ADRA1A (0.50) | KDM4ETDP1ALDH1A1MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805164-A2 | 6-(PYRIDINYL)-4-PYRIMIDONE DERIVATES AS TAU PROTEIN KINASE 1 INHIBITORS | Mitsubishi Pharma Corporation (JP) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006036015-A2 | 6- (PYRIDINYL) -4-PYRIMIDONE DERIVATES AS TAU PROTEIN KINASE 1 INHIBITORS | MITSUBISHI PHARMA CORPORATION (JP) | 2006-04-06 | — | — | WO | disclosed |