SCHEMBL5536934

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16877177	0.82	ALDH1A1 (0.70)	ALDH1A1LMNAL3MBTL1NPSR1MAPT
	SCHEMBL5546774	0.82	CYP1A2 (0.56)	ALDH1A1LMNAL3MBTL1NPSR1MAPT
	SCHEMBL5541058	0.82	ALDH1A1 (0.55)	HSD11B1ALDH1A1LMNAL3MBTL1NPSR1
	SCHEMBL5545310	0.81	HTT (0.60)	HSD11B1ALDH1A1LMNAL3MBTL1NPSR1
	SCHEMBL5546454	0.80	POLB (0.44)	HSD11B1ALDH1A1LMNAL3MBTL1HTT
	SCHEMBL9201834	0.77	HSD11B1 (0.54)	HSD11B1ALDH1A1LMNAL3MBTL1NPSR1
	SCHEMBL9201843	0.77	HSD11B1 (0.54)	HSD11B1ALDH1A1LMNAL3MBTL1NPSR1
	SCHEMBL5545724	0.72	KCNN4 (0.50)	—
	SCHEMBL5546087	0.72	HSD11B1 (0.50)	HSD11B1ALDH1A1LMNAL3MBTL1NPSR1
	SCHEMBL5546084	0.72	HSD11B1 (0.50)	HSD11B1ALDH1A1LMNAL3MBTL1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.