SCHEMBL5538015

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14562861	0.87	SERPINE1 (0.53)	LSSSCN9ASLC6A4ALDH1A1SMN1; SMN2
	SCHEMBL27629442	0.84	EPHX1 (0.50)	LSSSCN9ASLC6A4ALDH1A1SMN1; SMN2
	SCHEMBL27897594	0.81	SERPINE1 (0.48)	LSSSCN9ASLC6A4ALDH1A1TSHR
	SCHEMBL7390057	0.79	MTOR (0.55)	LSSALDH1A1HTTKDM4EMEN1
	SCHEMBL13074386	0.78	SLC6A4 (0.57)	LSSSLC6A4ALDH1A1TSHRSERPINE1
	SCHEMBL2056224	0.78	SLC6A4 (0.66)	LSSSLC6A4ALDH1A1TSHRSLC6A2
	SCHEMBL12039097	0.76	RIPK1 (0.58)	ALDH1A1SMN1; SMN2HTTKMT2ANPC1
	SCHEMBL5535914	0.76	GPBAR1 (0.46)	LSSSLC6A4ALDH1A1SERPINE1MEN1
	SCHEMBL1462002	0.75	NLRP3 (0.50)	ALDH1A1SMN1; SMN2TSHRMEN1KMT2A
	SCHEMBL13157801	0.75	SLC6A4 (0.54)	LSSSCN9ASLC6A4ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.