Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 11/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181173 | 0.92 | MAPT (0.46) | MMP14MAPTKMT2ANPC1RAB9A | |
| SCHEMBL532221 | 0.92 | MAPT (0.46) | MMP14MAPTKMT2ANPC1RAB9A | |
| SCHEMBL29712866 | 0.92 | MAPT (0.46) | MMP14MAPTKMT2ANPC1RAB9A | |
| Acrylic Acid SCHEMBL553534 | 0.91 | MMP14 (0.41) | MMP14MAPTKMT2ANPC1RAB9A | |
| Methacrylic Acid SCHEMBL554291 | 0.88 | MMP14 (0.51) | MMP14MAPTKMT2ANPC1RAB9A | |
| Methacrylic Acid SCHEMBL16715008 | 0.88 | MMP14 (0.51) | MMP14MAPTKMT2ANPC1RAB9A | |
| SCHEMBL5313230 | 0.86 | MAPT (0.49) | MMP14MAPTKMT2ANPC1RAB9A | |
| SCHEMBL5313232 | 0.86 | MAPT (0.49) | MMP14MAPTKMT2ANPC1RAB9A | |
| SCHEMBL15279797 | 0.85 | MMP14 (0.52) | MMP14MAPTKMT2ANPC1RAB9A | |
| SCHEMBL14254879 | 0.85 | MAPT (0.39) | MMP14MAPTKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035337-A1 | NANOHYBRID POLYMERS FOR OPHTHALMIC APPLICATIONS | KEY MEDICAL TECHNOLOGIES, INC. (US) | 2012-02-09 | — | — | US | claimed |
| EP-1802726-B1 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | ADVANCED POLYMERIK PTY LTD (AU) | 2011-11-30 | — | — | EP | claimed |
| US-8124188-B2 | Polymeric coatings and methods for forming them | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2012-02-28 | — | — | US | disclosed |
| US-20120041165-A1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-02-16 | — | — | US | disclosed |
| US-20120035337-A1 | NANOHYBRID POLYMERS FOR OPHTHALMIC APPLICATIONS | KEY MEDICAL TECHNOLOGIES, INC. (US) | 2012-02-09 | — | — | US | disclosed |
| EP-1802726-B1 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | ADVANCED POLYMERIK PTY LTD (AU) | 2011-11-30 | — | — | EP | disclosed |
| US-8048972-B2 | Nanohybrid polymers for ophthalmic applications | KEY MEDICAL TECHNOLOGIES, INC. (US) | 2011-11-01 | — | — | US | disclosed |
| EP-1740629-B1 | PHOTOCHROMIC COMPOSITIONS AND ARTICLES COMPRISING SILOXANE, ALKYLENE OR SUBSTITUTED ALKYLENE OLIGOMERS | ADVANCED POLYMERIK PTY LTD (AU) | 2011-03-30 | — | — | EP | disclosed |
| US-20110008265-A1 | In Situ Polymerization For Hair Treatment | LIVING PROOF, INC. (US) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110008265-A1 | In Situ Polymerization For Hair Treatment | PPOX, SUCLG1, GFER | MMP14 405/4885MAPT 470/4885KMT2A 3088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.