Methacrylic Acid

Methacrylic Acid

SCHEMBL554291

C=C(C)C(=O)O.CCN(CCO)c1ccc(/N=N/c2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP14 P50281 1/20 0.51
MAPT P10636 8/20 0.50
ALDH1A1 P00352 5/20 0.50
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
KMT2A Q03164 4/20 0.45
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
PSMD14 O00487 1/20 0.45
MITF O75030 1/20 0.45
MEN1 O00255 3/20 0.43
SMN1; SMN2 Q16637 4/20 0.41
MAPK1 P28482 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ALPL P05186 1/20 0.41
ALPI P09923 1/20 0.41
ALPG P10696 1/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL16715008 1.00 MMP14 (0.51) MMP14MAPTALDH1A1POLBGAA
SCHEMBL148266 0.91 MAPT (0.59) MMP14MAPTALDH1A1POLBGAA
SCHEMBL532332 0.91 MAPT (0.59) MMP14MAPTALDH1A1POLBGAA
Acrylic Acid SCHEMBL236630 0.89 MMP14 (0.51) MMP14MAPTALDH1A1POLBGAA
Methacrylic Acid SCHEMBL553839 0.88 MMP14 (0.41) MMP14MAPTALDH1A1POLBGAA
Methacrylic Acid SCHEMBL1462156 0.87 MMP14 (0.47) MMP14MAPTALDH1A1POLBGAA
SCHEMBL8422413 0.87 MAPT (0.56) MMP14MAPTALDH1A1POLBGAA
SCHEMBL29148022 0.85 MMP14 (0.55) MMP14MAPTALDH1A1POLBGAA
SCHEMBL20262011 0.85 MMP14 (0.55) MMP14MAPTALDH1A1POLBGAA
SCHEMBL8898982 0.83 MMP14 (0.58) MMP14MAPTALDH1A1POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120041165-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 2012-02-16 US claimed
US-20120035337-A1 NANOHYBRID POLYMERS FOR OPHTHALMIC APPLICATIONS KEY MEDICAL TECHNOLOGIES, INC. (US) 2012-02-09 US claimed
EP-1802726-B1 PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF ADVANCED POLYMERIK PTY LTD (AU) 2011-11-30 EP claimed
US-20150140267-A1 SURFACE PREPARATION METHOD ARKEMA FRANCE (FR) 2015-05-21 US disclosed
US-8124188-B2 Polymeric coatings and methods for forming them COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2012-02-28 US disclosed
US-20120041165-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 2012-02-16 US disclosed
US-20120035337-A1 NANOHYBRID POLYMERS FOR OPHTHALMIC APPLICATIONS KEY MEDICAL TECHNOLOGIES, INC. (US) 2012-02-09 US disclosed
EP-1802726-B1 PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF ADVANCED POLYMERIK PTY LTD (AU) 2011-11-30 EP disclosed
US-8048972-B2 Nanohybrid polymers for ophthalmic applications KEY MEDICAL TECHNOLOGIES, INC. (US) 2011-11-01 US disclosed
EP-1740629-B1 PHOTOCHROMIC COMPOSITIONS AND ARTICLES COMPRISING SILOXANE, ALKYLENE OR SUBSTITUTED ALKYLENE OLIGOMERS ADVANCED POLYMERIK PTY LTD (AU) 2011-03-30 EP disclosed
US-20110008265-A1 In Situ Polymerization For Hair Treatment LIVING PROOF, INC. (US) 2011-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110008265-A1 In Situ Polymerization For Hair Treatment PPOX, SUCLG1, GFER MMP14 405/4885MAPT 470/4885ALDH1A1 709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.