SCHEMBL5538533

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7613502	0.87	CALM1 (0.75)	CALM1IDH1PRSS1PRSS2PRSS3
	SCHEMBL13971231	0.87	CALM1 (0.75)	CALM1IDH1PRSS1PRSS2PRSS3
	SCHEMBL1807040	0.84	GRIN2D (0.42)	CALM1LOXL2ATMLMNA
	SCHEMBL5198189	0.83	SLC5A2 (0.42)	CALM1IDH1MTNR1AMTNR1BLTA4H
	SCHEMBL330370	0.82	CALM1 (0.67)	CALM1IDH1BCL2BCL2L1HNF4A
	SCHEMBL5543556	0.82	CALM1 (0.52)	CALM1IDH1PRSS1PRSS2PRSS3
	SCHEMBL5546859	0.81	MAOA (0.56)	LOXL2
	SCHEMBL28173954	0.79	CALM1 (0.80)	CALM1IDH1PRSS1PRSS2PRSS3
	SCHEMBL28202766	0.79	—	—
	SCHEMBL19313659	0.78	CALM1 (0.60)	CALM1IDH1PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.