SCHEMBL5543556

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5546491	0.84	CALM1 (0.60)	CALM1IDH1MAOAMAOBLTA4H
	SCHEMBL19313659	0.84	CALM1 (0.60)	CALM1MTNR1AMTNR1BIDH1PRSS1
	SCHEMBL13971231	0.83	CALM1 (0.75)	CALM1MTNR1AMTNR1BIDH1PRSS1
	SCHEMBL7613502	0.83	CALM1 (0.75)	CALM1MTNR1AMTNR1BIDH1PRSS1
	SCHEMBL5538533	0.82	CALM1 (0.57)	CALM1MTNR1AMTNR1BIDH1PRSS1
	SCHEMBL1048788	0.78	TAAR1 (0.62)	CALM1PRSS1PRSS2PRSS3LOXL2
	SCHEMBL5250636	0.78	MTNR1A (0.56)	CALM1MTNR1AMTNR1BIDH1PRSS1
	SCHEMBL5544652	0.78	AGXT (0.57)	MAOAMAOBBCL2
	SCHEMBL470	0.78	—	—
	SCHEMBL8092697	0.77	MTNR1A (0.54)	CALM1MTNR1AMTNR1BIDH1PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.