Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.74 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | RECQL | P46063 | 2/20 | 0.74 |
| ▸ | CASP6 | P55212 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | APEX1 | P27695 | 1/20 | 0.74 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.74 |
| ▸ | CA12 | O43570 | 4/20 | 0.66 |
| ▸ | CA9 | Q16790 | 4/20 | 0.66 |
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.59 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22581147 | 0.88 | KDM4E (0.57) | KDM4EL3MBTL1RXFP1POLBRECQL | |
| SCHEMBL5168401 | 0.87 | KMT2A (0.73) | KDM4EL3MBTL1RXFP1POLBRECQL | |
| SCHEMBL5159240 | 0.87 | KDM4E (0.56) | KDM4EL3MBTL1RXFP1POLBRECQL | |
| SCHEMBL1518037 | 0.86 | ALDH1A1 (0.68) | KDM4EL3MBTL1RXFP1POLBRECQL | |
| SCHEMBL14557599 | 0.85 | KDM4E (0.76) | KDM4EL3MBTL1RXFP1POLBRECQL | |
| SCHEMBL14159196 | 0.85 | POLB (0.63) | KDM4EL3MBTL1RXFP1POLBRECQL | |
| SCHEMBL1517977 | 0.82 | ALDH1A1 (0.65) | KDM4EL3MBTL1RXFP1POLBRECQL | |
| SCHEMBL32670799 | 0.81 | POLB (0.59) | KDM4EL3MBTL1RXFP1POLBRECQL | |
| SCHEMBL10061703 | 0.81 | CA9 (0.73) | KDM4EL3MBTL1RXFP1POLBRECQL | |
| SCHEMBL12581333 | 0.81 | KMT2A (0.76) | KDM4EL3MBTL1RXFP1POLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264126-A | Fluorescent probe based on methoxybenzothiophene derivative and preparation method and application thereof | 济宁医学院 | 2025-01-07 | — | — | CN | claimed |
| US-20070123514-A1 | Methods of modulating neurotrophin-mediated activity | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-05-31 | — | — | US | claimed |
| CN-119264126-A | Fluorescent probe based on methoxybenzothiophene derivative and preparation method and application thereof | 济宁医学院 | 2025-01-07 | — | — | CN | disclosed |
| US-20070123514-A1 | Methods of modulating neurotrophin-mediated activity | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-05-31 | — | — | US | disclosed |
| US-20070123514-A1 | Methods of modulating neurotrophin-mediated activity | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-05-31 | — | — | US | disclosed |
| US-20070123514-A1 | Methods of modulating neurotrophin-mediated activity | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-05-31 | — | — | US | disclosed |
| WO-2007030939-A2 | METHODS OF MODULATING NEUROTROPHIN-MEDIATED ACTIVITY | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123514-A1 | Methods of modulating neurotrophin-mediated activity | NGF, BDNF, NTRK2 | KDM4E 4479/4885L3MBTL1 4441/4885RXFP1 1070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.