Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.33 |
| ▸ | NEU1 | Q99519 | 2/20 | 0.32 |
| ▸ | NEU2 | Q9Y3R4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5546177 | 0.86 | TRPV1 (0.46) | AKT1NEU1NEU2CNR1CNR2 | |
| SCHEMBL5546611 | 0.86 | TRPV1 (0.46) | AKT1NEU1NEU2CNR1CNR2 | |
| SCHEMBL5540100 | 0.84 | AKT1 (0.39) | PAX8KDM4CKDM4APHF8KDM2A | |
| SCHEMBL5546192 | 0.84 | TRPV1 (0.43) | AKT1NEU1NEU2CNR1CNR2 | |
| SCHEMBL5546564 | 0.83 | PAX8 (0.43) | PAX8MEN1CYP2C19KMT2AEPHX2 | |
| SCHEMBL5546251 | 0.83 | PAX8 (0.43) | PAX8MEN1CYP1A2POLBCYP3A4 | |
| SCHEMBL5545009 | 0.83 | PAX8 (0.43) | PAX8MEN1POLBCYP3A4BLM | |
| SCHEMBL15355994 | 0.82 | PAX8 (0.45) | PAX8CYP2D6CYP2C19EPHX2 | |
| SCHEMBL5544835 | 0.82 | PAX8 (0.45) | PAX8CYP2D6CYP2C19EPHX2 | |
| SCHEMBL14450131 | 0.82 | PAX8 (0.45) | PAX8KDM4CKDM4APHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8951961-B2 | Structural and mechanistic basis for novel compound biosynthesis using 4-electron hexose oxidase | ACADEMIA SINICA (TW) | 2015-02-10 | — | — | US | disclosed |
| US-20130288955-A1 | STRUCTURAL AND MECHANISTIC BASIS FOR NOVEL COMPOUND BIOSYNTHESIS USING 4-ELECTRON HEXOSE OXIDASE | ACADEMIA SINICA (TW) | 2013-10-31 | — | — | US | disclosed |
| US-8507427-B2 | Structural and mechanistic basis for novel compound biosynthesis using the 4-electron hexose oxidase | ACADEMIA SINICA (TW) | 2013-08-13 | — | — | US | disclosed |
| US-20120108498-A1 | STRUCTURAL AND MECHANISTIC BASIS FOR NOVEL COMPOUND BIOSYNTHESIS USING THE 4-ELECTRON HEXOSE OXIDASE | ACADEMIA SINICA (TW) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108498-A1 | STRUCTURAL AND MECHANISTIC BASIS FOR NOVEL COMPOUND BIOSYNTHESIS USING THE 4-ELECTRON HEXOSE OXIDASE | G6PD, DHRS9, CYP2C9 | PAX8 4072/4885KDM4C 1190/4885KDM4A 1511/4885 |
| US-20130288955-A1 | STRUCTURAL AND MECHANISTIC BASIS FOR NOVEL COMPOUND BIOSYNTHESIS USING 4-ELECTRON HEXOSE OXIDASE | G6PD, CYP4X1, UGT1A9 | PAX8 4134/4885KDM4C 1244/4885KDM4A 1535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.