Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5540503 | 1.00 | KMT2A (0.38) | KMT2AALDH1A1MITFPKMSOS1 | |
| SCHEMBL5535404 | 0.86 | LMNA (0.39) | KMT2AALDH1A1MITFPKMSOS1 | |
| SCHEMBL5541257 | 0.86 | LMNA (0.39) | KMT2AALDH1A1MITFPKMSOS1 | |
| SCHEMBL5535399 | 0.86 | LMNA (0.39) | KMT2AALDH1A1MITFPKMSOS1 | |
| SCHEMBL5542812 | 0.84 | KMT2A (0.36) | KMT2AALDH1A1MITFPKM | |
| SCHEMBL5542819 | 0.84 | KMT2A (0.36) | KMT2AALDH1A1MITFPKM | |
| SCHEMBL5537119 | 0.83 | SOS1 (0.35) | KMT2AALDH1A1MITFPKMSOS1 | |
| SCHEMBL6010739 | 0.83 | SOS1 (0.35) | KMT2AALDH1A1MITFPKMSOS1 | |
| SCHEMBL14438025 | 0.82 | LMNA (0.50) | KMT2AALDH1A1MITFLMNAPOLB | |
| SCHEMBL6010636 | 0.81 | ALDH1A1 (0.43) | KMT2AALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |