Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5537119 | 1.00 | SOS1 (0.35) | SOS1KMT2AALDH1A1LMNAMITF | |
| SCHEMBL5541257 | 0.85 | LMNA (0.39) | SOS1KMT2AALDH1A1LMNAMITF | |
| SCHEMBL5535404 | 0.85 | LMNA (0.39) | SOS1KMT2AALDH1A1LMNAMITF | |
| SCHEMBL5535399 | 0.85 | LMNA (0.39) | SOS1KMT2AALDH1A1LMNAMITF | |
| SCHEMBL5535791 | 0.83 | KMT2A (0.33) | KMT2AALDH1A1LMNAMITFPKM | |
| SCHEMBL5535786 | 0.83 | KMT2A (0.33) | KMT2AALDH1A1LMNAMITFPKM | |
| SCHEMBL5540503 | 0.83 | KMT2A (0.38) | SOS1KMT2AALDH1A1LMNAMITF | |
| SCHEMBL5540508 | 0.83 | KMT2A (0.38) | SOS1KMT2AALDH1A1LMNAMITF | |
| SCHEMBL14438025 | 0.81 | LMNA (0.50) | KMT2AALDH1A1LMNAMITF | |
| SCHEMBL6010636 | 0.80 | ALDH1A1 (0.43) | KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | SOS1 768/4885KMT2A 4267/4885ALDH1A1 355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.