SCHEMBL5540567

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29661797	0.78	CCR1 (0.52)	ERN1KDM4EGPR3TOP2ACYP1A2
	SCHEMBL3156746	0.78	CCR1 (0.52)	ERN1KDM4EGPR3TOP2ACYP1A2
	SCHEMBL2927980	0.78	ERN1 (0.58)	ERN1KDM4EGPR3HTTLMNA
	SCHEMBL22744594	0.76	KDM4E (0.44)	ERN1KDM4EGPR3HTTALDH1A1
	SCHEMBL5537100	0.75	HTT (0.50)	ERN1KDM4EGPR3HTTLMNA
	SCHEMBL19044147	0.75	GPR3 (0.47)	ERN1KDM4EGPR3TOP2ACYP1A2
	SCHEMBL5540561	0.75	KDM4E (0.47)	ERN1KDM4EGPR3HTTALDH1A1
	SCHEMBL3151805	0.75	KDM4E (0.47)	KDM4EGPR3HTTALDH1A1HPGD
	SCHEMBL5517493	0.75	GPR3 (0.47)	ERN1KDM4EGPR3TOP2ACYP1A2
	SCHEMBL11295043	0.75	ERN1 (0.55)	ERN1KDM4EGPR3LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.