Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | PPM1A | P35813 | 1/20 | 0.36 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011089 | 0.81 | MEN1 (0.42) | ACHEKDM4EALDH1A1HTTLMNA | |
| SCHEMBL7044946 | 0.75 | ACHE (0.44) | ACHEKDM4EHTTLMNAHPGD | |
| Iodide SCHEMBL20636808 | 0.74 | ACHE (0.64) | ACHEKDM4EALDH1A1HTTMAPT | |
| SCHEMBL9010948 | 0.70 | MEN1 (0.40) | ACHEKDM4EALDH1A1HTTLMNA | |
| SCHEMBL146423 | 0.70 | ACHE (0.54) | ACHEHPGDPPM1A | |
| SCHEMBL22034130 | 0.69 | ACHE (0.68) | ACHEKDM4EALDH1A1HTTMAPT | |
| Ammonia Solution, Strong SCHEMBL30096047 | 0.69 | ACHE (0.53) | ACHEHPGDPPM1A | |
| Water SCHEMBL436371 | 0.69 | ACHE (0.53) | ACHEHPGDPPM1A | |
| SCHEMBL17187153 | 0.69 | ACHE (0.53) | ACHE | |
| Ammonia Solution, Strong SCHEMBL28899074 | 0.69 | ACHE (0.53) | ACHEHPGDPPM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1088229-A4 | HIGH THROUGHPUT METHODS, SYSTEMS AND APPARATUS FOR PERFORMING CELL BASED SCREENING ASSAYS | CALIPER TECHN CORP (US) | 2002-05-08 | — | — | EP | claimed |
| EP-1088229-A1 | HIGH THROUGHPUT METHODS, SYSTEMS AND APPARATUS FOR PERFORMING CELL BASED SCREENING ASSAYS | Caliper Technologies Corporation (US) | 2001-04-04 | — | — | EP | claimed |
| WO-1999067639-A1 | HIGH THROUGHPUT METHODS, SYSTEMS AND APPARATUS FOR PERFORMING CELL BASED SCREENING ASSAYS | CALIPER TECHNOLOGIES CORPORATION (US) | 1999-12-29 | — | — | WO | claimed |
| US-12083165-B2 | Thymosin alpha 1 for use in treatment of cystic fibrosis | SCICLONE PHARMACEUTICALS INTERNATIONAL (SG) PTE. LTD. (SG) | 2024-09-10 | — | — | US | disclosed |
| US-20230173031-A1 | THYMOSIN ALPHA 1 FOR USE IN TREATMENT OF CYSTIC FIBROSIS | SCICLONE PHARMACEUTICALS INTERNATIONAL (SG) PTE. LTD. (SG) | 2023-06-08 | — | — | US | disclosed |
| US-11524056-B2 | Thymosin alpha 1 for use in treatment of cystic fibrosis | SCICLONE PHARMACEUTICALS INTERNATIONAL LTD. (KY) | 2022-12-13 | — | — | US | disclosed |
| CN-107466236-B | Use of thymosin alpha 1 for the treatment of cystic fibrosis | 赛生药品股份国际有限公司 | 2021-10-26 | — | — | CN | disclosed |
| EP-3865149-A1 | THYMOSIN ALPHA 1 FOR USE IN TREATMENT OF CYSTIC FIBROSIS | SciClone Pharmaceuticals International Ltd. (KY) | 2021-08-18 | — | — | EP | disclosed |
| EP-3256150-B1 | THYMOSIN ALPHA 1 FOR USE IN TREATMENT OF CYSTIC FIBROSIS | SCICLONE PHARMACEUTICALS INT LTD (KY) | 2020-12-09 | — | — | EP | disclosed |
| US-10478474-B2 | Thymosin alpha 1 for use in treatment of cystic fibrosis | SciClone Pharmaceuticals International, Ltd. (KY) | 2019-11-19 | — | — | US | disclosed |
| EP-1179087-B1 | FOCUSING OF MICROPARTICLES IN MICROFLUIDIC SYSTEMS | CALIPER LIFE SCIENCES INC (US) | 2019-03-27 | — | — | EP | disclosed |
| WO-2001079522-A2 | SCREENING ASSAY METHODS AND SYSTEMS USING TARGET POOLING | CALIPER TECHNOLOGIES CORP. (US) | 2001-10-25 | — | — | WO | disclosed |
| EP-1147417-A1 | DEVICES, SYSTEMS AND METHODS FOR TIME DOMAIN MULTIPLEXING OF REAGENTS | Caliper Technologies Corporation (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000045172-A9 | DEVICES, SYSTEMS AND METHODS FOR TIME DOMAIN MULTIPLEXING OF REAGENTS | CALIPER TECHN CORP (US) | 2001-10-11 | — | — | WO | disclosed |
| EP-1088229-A1 | HIGH THROUGHPUT METHODS, SYSTEMS AND APPARATUS FOR PERFORMING CELL BASED SCREENING ASSAYS | Caliper Technologies Corporation (US) | 2001-04-04 | — | — | EP | disclosed |
| WO-2000070080-A1 | FOCUSING OF MICROPARTICLES IN MICROFLUIDIC SYSTEMS | CALIPER TECHNOLOGIES CORP. (US) | 2000-11-23 | — | — | WO | disclosed |
| WO-2000045172-A1 | DEVICES, SYSTEMS AND METHODS FOR TIME DOMAIN MULTIPLEXING OF REAGENTS | CALIPER TECHNOLOGIES CORP. (US) | 2000-08-03 | — | — | WO | disclosed |
| WO-1999067639-A1 | HIGH THROUGHPUT METHODS, SYSTEMS AND APPARATUS FOR PERFORMING CELL BASED SCREENING ASSAYS | CALIPER TECHNOLOGIES CORPORATION (US) | 1999-12-29 | — | — | WO | disclosed |
| WO-1998037878-A9 | METHODS AND COMPOSITIONS FOR TREATING CYSTIC FIBROSIS | — | 1999-02-11 | — | — | WO | disclosed |
| WO-1998037878-A1 | METHODS AND COMPOSITIONS FOR TREATING CYSTIC FIBROSIS | GENZYME CORPORATION (US) | 1998-09-03 | — | — | WO | disclosed |